Results 71 to 80 of about 17,232,733 (275)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Operationalising social‐ecological systems to meet complex sustainability challenges posed by widespread biological invasions

open access: yesPeople and Nature
Biological invasions are a major driver of biodiversity loss worldwide. The scale and pace of these invasions often exceed resources available for control, necessitating long‐term management strategies that balance complex sustainability goals.
Fabian C. Kyne   +4 more
doaj   +1 more source

Biomedical research at the Population Council [PDF]

open access: yes, 2015
IN THIS ISSUE: Research and development to improve reproductive health | From bench to bedroom: Biomedical research at the Population Council | Male contraception in discovery | Multipurpose prevention technologies in early-stage development ...
Population Council
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

On aggregative economic models and population policy [PDF]

open access: yes, 1971
For more about the East-West Center, see http://www.eastwestcenter.org/The aim of this paper is to set out the requirements of a theory of optimal economic--demographic growth. There are three sections.
McNicoll, Geoffrey   +1 more
core   +1 more source

Population Briefs, Vol. 13, no. 1 [PDF]

open access: yes, 2007
IN THIS ISSUE: Chemical postmaster helps deliver contraceptive to testis | Complex role for marriage in HIV risk, studies find | Examining the rollout of pediatric antiretroviral treatment in South Africa | Focused antenatal care acceptable, tricky to ...
Population Council
core   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Neoclassical growth models and the optimum rate of population growth (with applications to underdeveloped countries) [PDF]

open access: yes, 1970
For more about the East-West Center, see http://www.eastwestcenter.org/Among economists who are also interested in demography, there is a respectable tradition of analysis revolving around the concept of a static optimum population. The work of W.
Crouch, Robert L.   +1 more
core   +1 more source

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