Results 71 to 80 of about 17,232,733 (275)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Biological invasions are a major driver of biodiversity loss worldwide. The scale and pace of these invasions often exceed resources available for control, necessitating long‐term management strategies that balance complex sustainability goals.
Fabian C. Kyne +4 more
doaj +1 more source
Biomedical research at the Population Council [PDF]
IN THIS ISSUE: Research and development to improve reproductive health | From bench to bedroom: Biomedical research at the Population Council | Male contraception in discovery | Multipurpose prevention technologies in early-stage development ...
Population Council
core +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
On aggregative economic models and population policy [PDF]
For more about the East-West Center, see http://www.eastwestcenter.org/The aim of this paper is to set out the requirements of a theory of optimal economic--demographic growth. There are three sections.
McNicoll, Geoffrey +1 more
core +1 more source
Population Briefs, Vol. 13, no. 1 [PDF]
IN THIS ISSUE: Chemical postmaster helps deliver contraceptive to testis | Complex role for marriage in HIV risk, studies find | Examining the rollout of pediatric antiretroviral treatment in South Africa | Focused antenatal care acceptable, tricky to ...
Population Council
core +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
The human gut microbiome across the life course
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Neoclassical growth models and the optimum rate of population growth (with applications to underdeveloped countries) [PDF]
For more about the East-West Center, see http://www.eastwestcenter.org/Among economists who are also interested in demography, there is a respectable tradition of analysis revolving around the concept of a static optimum population. The work of W.
Crouch, Robert L. +1 more
core +1 more source

