Results 121 to 130 of about 2,505,274 (300)

Urban Decline and Durable Housing [PDF]

People continue to live in many big American cities, because in those cities housing costs less than new construction. While cities may lose their productive edge, their houses remain and population falls only when housing depreciates.
Edward L. Glaeser, Joseph Gyourko
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CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Habitat characteristics and the rate of decline in a threatened farmland bird, the ortolan bunting Emberiza hortulana

Journal of Avian Biology
Farmland habitats witness steep declines in biodiversity. One rapidly declining farmland species is the ortolan bunting Emberiza hortulana. In Finland, a staggering 99% of the population has been lost during the past 30 years.
Sirke Piirainen, Tuomas Seimola, Andreas Lindén, Juha Tiainen, Markus Piha   +4 more
doaj   +1 more source

Conservation genomic study of Hopea hainanensis (Dipterocarpaceae), an endangered tree with extremely small populations on Hainan Island, China

Frontiers in Plant Science
IntroductionHopea hainanensis Merrill & Chun is considered a keystone and indicator species in the tropical lowland rainforests of Hainan Island. Owing to its high-quality timber, H.
Liang Tang, Liang Tang, Jun-qiao Long, Hai-ying Wang, Chao-kang Rao, Wen-xing Long, Li Yan, Yong-bo Liu   +7 more
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

2000-2009 Population Growth in the Midwest: Urban and Rural Dimensions [PDF]

This report examines the rural-urban dimensions of recent population change across a 12-state region that includes Illinois, Indiana, Iowa, Kansas, Michigan, Minnesota, Missouri, Nebraska, North Dakota, Ohio, South Dakota, and Wisconsin. Using annual ...
Eathington, Liesl
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Decline in sea otter (Enhydra lutris) populations along the Alaska Peninsula, 1986–2001 [PDF]

, 2005
During the 1990s, sea otter (Enhydra lutris) counts in the Aleutian archipelago decreased by 70% throughout the archipelago between 1992 and 2000. Recent aerial surveys in the Aleutians did not identify the eastward extent of the decline; therefore we ...
Burn, Douglas M., Doroff, Angela M.
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Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Fungal Microbiome of Alive and Dead Korean Fir in its Native Habitats

Mycobiology
A rapid decline of Abies koreana has been reported in most of the natural alpine habitats in Korea. It is generally accepted that this phenomenon is due to climate change even though no clear conclusions have been drawn.
Young-Hyun You, Jong Myong Park, Youn-Bong Ku, Tae-Yong Jeong, Kyeongmo Lim, Jae-Ho Shin, Jin-Suk Kim, Ji Won Hong   +7 more
doaj   +1 more source

Nursing home bed capacity in the States, 1978-86. [PDF]

, 1988
Trends in nursing home bed supply in the States show large variations in beds per population and a gradual decline in supply per aged population. A cross-sectional time-series regression analysis was used to examine some factors associated with nursing ...
Grant, LA, Harrington, C, Swan, JH
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