Results 171 to 180 of about 3,143,816 (338)

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Prehospital time intervals for trauma patients according to population density levels in Sweden; a national retrospective cohort study. [PDF]

Scand J Trauma Resusc Emerg Med
Lundberg OHM, Lapidus O, Bäckström D.
europepmc   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Habitat use, selection, and population density of chameleon communities (Calumma spp.) in the fragmented central highlands forests of Madagascar. [PDF]

BMC Ecol Evol
Rakotoarimalala F, Kuhn AL, Raselimanana AP, Jacquis AT, Ruane S.   +4 more
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Stretching Out: Leopard Home-Range Expansion in Response to Suppressed Population Density in a Recovering Post-War Landscape. [PDF]

Ecol Evol
Briers-Louw WD, Kendon T, Hayes A, Gaynor D, Naude V.   +4 more
europepmc   +1 more source

POPULATION DENSITY STUDY. [PDF]

, 1968
Vandevender, S.G., Lindberg, R.C.
openaire   +2 more sources

Habitat and density effects on the demography of an expanding wolf population in Central Europe

Aimara Planillo, Ilka Reinhardt, Gesa Kluth, Sebastian Collet, Gregor Rolshausen, Carsten Nowak, Katharina Steyer, Götz Ellwanger, Stephanie Kramer‐Schadt   +8 more
openalex   +1 more source

Interplay between RNA‐protein interactions and RNA structures in gene regulation

FEBS Open Bio, EarlyView.
Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko, Mauro Scaravilli, Minna‐Liisa Änkö   +2 more
wiley   +1 more source

Socioeconomic inequalities in waist circumference and its 12-year change: Moderation by neighbourhood population density. [PDF]

Prev Med Rep
Selvakumaran S, Chandrabose M, Hadgraft N, Owen N, Sugiyama T.   +4 more
europepmc   +1 more source