Results 31 to 40 of about 1,243,397 (260)

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Studying the water crisis in Delhi due to rapid urbanisation and land use transformation

International Journal of Urban Sustainable Development, 2021
The paper records the spatial dynamics and water consumption pattern through statistical and spatial evidence. The objective of this paper is to analyse the impact of land use land cover change on water demand and supply pattern of a rapidly growing ...
Arindam Biswas, Druti Gangwar
doaj   +1 more source

The role and implications of mammalian cellular circadian entrainment

FEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Developmental and genetic effects on behavioral and life‐history traits in a field cricket

Ecology and Evolution, 2019
A fundamental goal of evolutionary ecology is to identify the sources underlying trait variation on which selection can act. Phenotypic variation will be determined by both genetic and environmental factors, and adaptive phenotypic plasticity is expected
Tina W. Wey, Denis Réale, Clint D. Kelly   +2 more
doaj   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Airborne Lidar Survey, Density-Based Clustering, and Ancient Maya Settlement in the Upper Usumacinta River Region of Mexico and Guatemala

Remote Sensing, 2021
We present results from the archaeological analysis of 331 km2 of high-resolution airborne lidar data collected in the Upper Usumacinta River basin of Mexico and Guatemala.
Charles Golden, Andrew K. Scherer, Whittaker Schroder, Timothy Murtha, Shanti Morell-Hart, Juan Carlos Fernandez Diaz, Socorro del Pilar Jiménez Álvarez, Omar Alcover Firpi, Mark Agostini, Alexandra Bazarsky, Morgan Clark, G. Van Kollias, Mallory Matsumoto, Alejandra Roche Recinos, Joshua Schnell, Bethany Whitlock   +15 more
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Estimating density of an unmarked, low‐density wild turkey population

Ecosphere
Eastern wild turkey (Meleagris gallopavo silvestris, hereafter turkey) populations have been declining across the southeastern United States, including Oklahoma.
Molly M. Koeck, Anna K. Moeller, R. Dwayne Elmore, M. Colter Chitwood   +3 more
doaj   +1 more source

Time‐traveling larvae ensure survival in small, synchronously fluctuating populations

Ecosphere, 2020
Population structure is an important aspect of patchily distributed organisms. Small local populations, large temporal fluctuations, synchronized dynamics, and low migration rates should all lead to lowered rates of patch occupancy and increased ...
Christer Solbreck, Olof Widenfalk
doaj   +1 more source