Results 111 to 120 of about 3,976,266 (254)

Expert Group Meeting on Population, Environment and Sustainable Development : selected papers of the Pre-conference Seminar Fourth Asian and Pacific Population Conference, Jomtien, Thailand, 13-18 May 1991 [PDF]

, 1994
The Fourth Asian and Pacific Population Conference, a ministerial level meeting, was organized jointly by ESCAP and the United Nations Population Fund (UNFPA) and hosted by the Government of Indonesia.
United Nations Development Programme (UNDP), UN.ESCAP   +1 more
core  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Nationwide projections of heat- and cold-related mortality impacts under various climate change and population development scenarios in Switzerland. [PDF]

Environ Res Lett, 2023
de Schrijver E, Sivaraj S, Raible CC, Franco OH, Chen K, Vicedo-Cabrera AM.   +5 more
europepmc   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Population development and landscape preference of reintroduced wild ungulates: successful rewilding in Southern Italy. [PDF]

PeerJ, 2022
Rivieccio E, Troiano C, Petrelli S, Maselli V, de Filippo G, Fulgione D, Buglione M.   +6 more
europepmc   +1 more source

Population headliners. No.295, July-August 2003 [PDF]

, 2003
The newsletter is produced with support from the United Nations Population Fund (UNFPA), Project No. RAS5P203United Nations Population Fund (UNFPA)• Beijing eases birth control policy ...2 • UNFPA meets regional partners ...3 • Myanmar Fertility and ...
United Nations Population Fund (UNFPA), UN.ESCAP   +1 more
core  

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Soybean Cyst Nematode Population Development and its Effect on Pennycress in a Greenhouse Study. [PDF]

J Nematol, 2022
Hoerning C, Chen S, Frels K, Wyse D, Wells S, Anderson J.   +5 more
europepmc   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Exploring the Dependence and Influencing Factors of Carbon Emissions from the Perspective of Population Development. [PDF]

Int J Environ Res Public Health, 2021
Zhao K, Cui X, Zhou Z, Huang P, Li D.
europepmc   +1 more source