Risk prediction of sarcopenia in a large health checkup population: development and validation of a dynamic online nomogram. [PDF]
Yang H, Luo C, Xiao Q, Luo K, Shen N.
europepmc +1 more source
Long-term sickness absence in a working population: development and validation of a risk prediction model in a large Dutch prospective cohort. [PDF]
van der Burg LRA +8 more
europepmc +1 more source
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski +12 more
wiley +1 more source
Novel perpetual genetic population development and genome assembly of superior maize inbred lines provide insights into genetic improvement. [PDF]
Xue Y +12 more
europepmc +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
A bayesian network model for neurocognitive disorders digital screening in Chinese population: development and validation study. [PDF]
Yu Y, Zhang S, Li H, Xue F.
europepmc +1 more source
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
The Population Development of the Red Mason Bee, Osmia bicornis L., for Different Types of Nesting Materials. [PDF]
Zajdel B +3 more
europepmc +1 more source
Astrocyte heterogeneity in brain metastases
Astrocytes emerge as pivotal regulators of metastatic colonization, survival, immune remodeling, and therapy response associated with an increasing heterogeneity that requires spatially and longitudinally resolved approaches to uncover regulatory programs and guide context‐specific therapies.
Carolina Hernández‐Oliver +2 more
wiley +1 more source

