Results 191 to 200 of about 2,912,298 (341)

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Woodward et al. 1D Excitable Plankton Model Code from Physical flow effects can dictate plankton population dynamics

, 2019
J. R. Woodward, Jonathan W. Pitchford, M. A. Bees   +2 more
openalex   +1 more source

Climate-associated changes in prey availability drive reproductive dynamics of the North Atlantic right whale population [PDF]

, 2015
Erin Meyer‐Gutbrod, C T Greene, P. Sullivan, AJ Pershing   +3 more
openalex   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source

Longevity in plants impacts phylogenetic and population dynamics. [PDF]

New Phytol
Smith SA, Pease JB, Carruthers T, Bradburd GS, Huegele IB, Stull GW, Weaver WN, Yang Y, Yi TS, Beaulieu JM.   +9 more
europepmc   +1 more source

Population dynamics of Trichiurus lepturus (Linnaeus, 1758) off Veraval [PDF]

, 2014
R. Avinash, AS Desai, Shubhadeep Ghosh
openalex  

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Drivers of population dynamics and juvenile mortality in Northwest Atlantic harp seals. [PDF]

Ecol Appl
Tinker MT, Stenson GB, Mosnier A, Van de Walle J, Lang SLC, Hammill MO.   +5 more
europepmc   +1 more source

Community-based monitoring of vector control interventions impact upon mosquito population dynamics in rural Zambia

, 2015
Chadwick Sikaala
openalex   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source