Results 121 to 130 of about 7,075,558 (291)

Programmatic mapping and estimating the population size of female sex workers, men who have sex with men, people who inject drugs and transgender populations in Kenya [version 4; peer review: 2 approved, 1 approved with reservations]

Gates Open Research
Introduction Effective coverage of Human Immunodeficiency Virus prevention services for Key Populations (KPs) including female sex workers (FSWs), men who have sex with men (MSM), people who inject drugs (PWID) and transgender (TG) people necessitates ...
Faran Emmanuel, Helgar Musyoki, Parinita Bhattacharjee, Janet Musimbi, Mary Mugambi, Japheth Kioko, Shajy Isac, Shem Kaosa, Solomon Wambua, Diane Aluko, Ravi Prakash, Waruiru Wanjiru   +11 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Uncovering large inconsistencies between machine learning derived gridded settlement datasets

EPJ Data Science
High-resolution human settlement maps provide detailed delineations of where people live and are vital for scientific and practical purposes, such as rapid disaster response, allocation of humanitarian resources, and international development.
Vedran Sekara, Andrea Martini, Manuel Garcia-Herranz, Do-Hyung Kim   +3 more
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Population Estimates for Oregon: July 1, 1995 [PDF]

, 1996
This report provides population estimates for Oregon, its counties, and cities for the years 1980 through 1995. As mandated by Oregon law (ORS 190.510 to 190.610), the Center for Population Research and Census at Portland State University acting on ...
Population Research Center, Portland State University, Wineberg, Howard   +1 more
core   +1 more source

Revisiting Assumptions that Underlie Estimates of Proportional Entrainment of Delta Smelt by State and Federal Water Diversions from the Sacramento-San Joaquin Delta

San Francisco Estuary and Watershed Science, 2011
The delta smelt is a small, endemic fish that resides in the upper San Francisco Estuary. They are listed under state and federal Endangered Species Acts. Since 2002, their abundance has been at record low levels.
William J. Miller
doaj  

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

More insightful scientific estimates about population members’ gains

Social Sciences and Humanities Open
Because they sometimes conflate basic and applied research goals, social scientists rely on problematic null hypothesis statistical testing (NHST) to decide their empirical studies' theoretical and practical implications.
David Trafimow, Michael R. Hyman
doaj   +1 more source

‘Guide and Prejudice’— How Argonautes recognize targets across domains of life

FEBS Letters, EarlyView.
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley   +1 more source