Results 71 to 80 of about 1,237,731 (267)

Estimating recent fertility from data on own children : West Malaysia, 1958-67 [PDF]

open access: yes, 1970
For more about the East-West Center, see http://www.eastwestcenter.org/Vital registration, hence knowledge of fertility, remains notoriously deficient in many nations of the world.
East-West Population Institute   +1 more
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Population Estimates of Counties and Incorporated Cities of Oregon

open access: yes, 1962
Population enumerations and estimates for counties and incorporated cities of Oregon for 1962-1974. Through 1966 as: Certificate of population enumerations and estimates of counties and incorporated cities of ...
Portland State University. Population Research Center
core  

Subnational population estimates: at 30 June 2014 [PDF]

open access: yes, 2014
Of New Zealand\u27s 16 regions, only Auckland and Canterbury\u27s population growth rate was above the national average, according to this report.

core  

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Population Estimates for Oregon: July 1, 1995

open access: yes, 1995
This report provides population estimates for Oregon, its counties, and cities for the years 1980 through 1995. As mandated by Oregon law (ORS 190.510 to 190.610), the Center for Population Research and Census at Portland State University acting on ...
Population Research Center, Portland State University   +1 more
core  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Certified 2014 Population Estimates for Oregon and Counties

open access: yes, 2014
Certified Population Estimates for Oregon and Its Counties.
Portland State University. Population Research Center
core  

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Home - About - Disclaimer - Privacy