Results 111 to 120 of about 1,325,954 (330)

Conditioning the logistic branching process on non-extinction

, 2013
We consider a birth and death process in which death is due to both `natural death' and to competition between individuals, modelled as a quadratic function of population size.
Etheridge, Alison, Wang, Shidong, Yu, Feng   +2 more
core  

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

Molecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

GENETICS OF NATURAL POPULATIONS. XVI. ALTITUDINAL AND SEASONAL CHANGES PRODUCED BY NATURAL SELECTION IN CERTAIN POPULATIONS OF DROSOPHILA PSEUDOOBSCURA AND DROSOPHILA PERSIMILIS [PDF]

, 1948
Theodosius Dobzhansky
openalex   +1 more source

Discrete Feynman-Kac formulas for branching random walks

, 2012
Branching random walks are key to the description of several physical and biological systems, such as neutron multiplication, genetics and population dynamics.
A. Mazzolo, A. Zoia, Bailey N. T. J., Brunet E., Bénichou O., Derrida B., E. Dumonteil, Harris T. E., Jagers P., Kac M., Majumdar S. N., Mazzolo A., Pitman J., Pázsit I.   +13 more
core   +1 more source

EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines

Molecular Oncology, EarlyView.
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche, Renske Imschoot, Béatrice Lintermans, Lode Denolf, Joachim Taminau, Charlotte Fieuws, Geert Berx, Kris Gevaert, Kathleen B. M. Claes   +8 more
wiley   +1 more source

Polygenic scores for longitudinal prediction of incident type 2 diabetes in an ancestrally and medically diverse primary care physician network: a patient cohort study

Genome Medicine
Background The clinical utility of genetic information for type 2 diabetes (T2D) prediction with polygenic scores (PGS) in ancestrally diverse, real-world US healthcare systems is unclear, especially for those at low clinical phenotypic risk for T2D ...
Ravi Mandla, Philip Schroeder, Bianca Porneala, Jose C. Florez, James B. Meigs, Josep M. Mercader, Aaron Leong   +6 more
doaj   +1 more source

Quantitative Genetics of Populations [PDF]

, 1955
G. Pontecorvo
openalex   +1 more source

Efficient Forward Simulation of Fisher-Wright Populations with Stochastic Population Size and Neutral Single Step Mutations in Haplotypes

, 2012
In both population genetics and forensic genetics it is important to know how haplotypes are distributed in a population. Simulation of population dynamics helps facilitating research on the distribution of haplotypes.
Andersen, Mikkel Meyer, Eriksen, Poul Svante   +1 more
core  

Implications of fisheries during the spawning season for the sustainable management and recovery of depleted fish stocks: a conceptual framework [PDF]

, 2009
Fishing during the spawning season may negatively affects the reproductive potential and reproductive dynamics of exploited fish stocks due to a variety of mechanisms such as the disturbance of the natural spawning behaviour, effects on the age, size and
Rijnsdorp, A.D.
core   +1 more source

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

Molecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner, Markus Eckstein, Christoph Mark, Matthias W. Beckmann, Arndt Hartmann, Pamela L. Strissel, Reiner Strick   +6 more
wiley   +1 more source