Results 121 to 130 of about 1,325,954 (330)

GENETICS OF NATURAL POPULATIONS. XXXV. A PROGRESS REPORT ON GENETIC CHANGES IN POPULATIONS OFDROSOPHILA PSEUDOOBSCURAIN THE AMERICAN SOUTHWEST [PDF]

, 1964
Th. Dobzhansky, Wyatt W. Anderson, Olga Pavlovsky, B Spassky, Christopher Wills   +4 more
openalex   +1 more source

EGFR‐STAT3 activation provides a therapeutic rationale for targeting aggressive ETV1‐positive prostate cancer

Molecular Oncology, EarlyView.
Cotargeting EGFR and STAT3 with Erlotinib and TTI‐101 impairs both 2D and 3D growth of ETV1‐overexpressing prostate cancer cells by disrupting a self‐sustaining ETV1–EGFR positive feedback loop that promotes EGFR and STAT3 expression and phosphorylation (activation).
Elsa Gomes Paiva, Bernardo Orr, Ana Azeredo, Andreia Brandão, Manuel R. Teixeira, Paula Paulo   +5 more
wiley   +1 more source

Population genetics: An introduction for physicists

SciPost Physics Lecture Notes
Population genetics lies at the heart of evolutionary theory. This topic forms part of many biological science curricula but is rarely taught to physics students.
Andrea Iglesias-Ramas, Samuele Pio Lipani, Rosalind J. Allen
doaj   +1 more source

THE ECOLOGICAL GENETICS OF THE MUTANT SOOTY IN POPULATIONS OF TRIBOLIUM CASTANEUM , [PDF]

, 1963
Gunther Schlager
openalex   +1 more source

Association of high‐dose radioactive iodine therapy with PPM1D‐mutated clonal hematopoiesis in older individuals

Molecular Oncology, EarlyView.
In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim, Sungwoo Bae, Jaeyong Choi, Sun‐Wha Im, Bukyoung Cha, Gyeongseo Jung, Sun Wook Cho, Eul‐Ju Seo, Young Ah Lee, Jin Chul Paeng, Young Joo Park, Jong‐Il Kim   +11 more
wiley   +1 more source

Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management

Molecular Oncology, EarlyView.
DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez, Asieh Naderi, Kim‐Tuyen Huynh‐Dam, Vitali Sikirzhytski, Ioulia Chatzistamou, Hippokratis Kiaris   +5 more
wiley   +1 more source

Population Genetics and Ecology. [PDF]

Biometrics, 1976
Eviatar Nevo, Joseph Felsenstein, Samuel Karlin   +2 more
openaire   +3 more sources

Machine learning for identifying liver and pancreas cancers through comprehensive serum glycopeptide spectra analysis: a case‐control study

Molecular Oncology, EarlyView.
This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima, Yuko Takami, Ken Kawabe, Kazuhiro Tanabe, Chihiro Hayashi, Mikio Mikami, Tetsuya Kusumoto   +6 more
wiley   +1 more source

GENETICS OF NATURAL POPULATIONS. XXXVII. THE COADAPTED SYSTEM OF CHROMOSOMAL VARIANTS IN A POPULATION OF DROSOPHILA PSEUDOOBSCURA [PDF]

, 1966
Olga Pavlovsky, Th. Dobzhansky
openalex   +1 more source

Population genetics of Lithuanians

Annals of Human Biology, 2001
The primary objective of this article was to overview the present-day knowledge on genetic features of the Lithuanian population. Genetic differentiation within the Lithuanian population and the relationship between Lithuanians and other European populations was analysed by means of blood groups, serum protein polymorphisms and DNA markers including ...
openaire   +3 more sources