Results 131 to 140 of about 7,466,882 (388)

Adaptive non-uniform mutation based on statistics for genetic algorithms [PDF]

, 2002
Copyright @ 2002 ACMAs a meta-heuristic search algorithm based on mechanisms abstracted from population genetics, the genetic algorithm (GA) implicitly maintains the statistics about the search space through the population.
Yang, S
core  

Structure and expression of dog apolipoprotein A-I, E, and C-I mRNAs: implications for the evolution and functional constraints of apolipoprotein structure.

Journal of Lipid Research, 1989
Dog apolipoprotein (apo) C-I, A-I, and E cDNA clones were identified in a dog liver cDNA library in lambda gt10 by hybridization to synthetic oligonucleotide probes with the corresponding human DNA sequences. The longest clone for each apolipoprotein was
C C Luo, W H Li, L Chan
doaj  

Genetic and phenotypic variability of iris color in Buenos Aires population

Genetics and Molecular Biology
The aim of this work was to describe the phenotypic and genotypic variability related to iris color for the population of Buenos Aires province (Argentina), and to assess the usefulness of current methods of analysis for this country.
Diana María Hohl, Brenda Bezus, Julia Ratowiecki, Cecilia Inés Catanesi   +3 more
doaj   +1 more source

Quantitative Genetics of Populations [PDF]

, 1955
G. Pontecorvo
openalex   +1 more source

Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer

Molecular Oncology, EarlyView.
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte, Osheen Sharma, Laura Leuenberger, Emelie Wallin, Josefin Fernebro, Päivi Östling, Rebecka Bergström, Johan Lindberg, Ulrika Joneborg, Olli Kallioniemi, Brinton Seashore‐Ludlow   +10 more
wiley   +1 more source

Population Genetics Data of 21 Autosomal STR Loci in the Romanian Population

Data
This study aimed to determine the allele frequencies and genetic diversity of 21 autosomal short tandem repeat (STR) loci from the Expanded U.S. Core Loci and European Standard Set in the Romanian population. A random sample of 928 unrelated men from all
George Popoiu, Florin Stanciu, Veronica Cuțăr, Simona Vladu, Paulina Podgoreanu, Violeta Nicola, Ionel Marius Stoian, Anastasia Procopciuc, Bogdan Hațegan, Bogdan Negoiță, Alis Mihaela Păunache, Adnana Cotolea, Ana Rădulescu, Adrian Constantin Hubca, Sergiu Emil Georgescu   +14 more
doaj   +1 more source

Comprehensive omics‐based classification system in adult patients with B‐cell acute lymphoblastic leukemia

Molecular Oncology, EarlyView.
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song, Ting Liu, Qishan Hao, Qiuyun Fang, Xiaoyuan Gong, Yan Li, Zheng Tian, Hui Wei, Min Wang, Jianxiang Wang, Tao Cheng, Yingchang Mi   +11 more
wiley   +1 more source

The role of cell cycle-related genes in the tumorigenesis of adrenal and thyroid neuroendocrine tumors

Heliyon
The molecular mechanisms underlying adrenal and thyroid neuroendocrine tumors, including their tumorigenesis, progression, and metastasis, involve unique pathways regulating cell cycle progression.
Ekaterina Filipovich, Ekaterina Gorodkova, Anastasia Shcherbakova, Walaa Asaad, Sergey Popov, Galina Melnichenko, Natalya Mokrysheva, Marina Utkina   +7 more
doaj  

GENETICS OF NATURAL POPULATIONS. XXXVII. THE COADAPTED SYSTEM OF CHROMOSOMAL VARIANTS IN A POPULATION OF DROSOPHILA PSEUDOOBSCURA [PDF]

, 1966
Olga Pavlovsky, Th. Dobzhansky
openalex   +1 more source

Circulating tumor DNA monitoring and blood tumor mutational burden in patients with metastatic solid tumors treated with atezolizumab

Molecular Oncology, EarlyView.
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton, Russell W. Madison, Candice Francheska B. Tambaoan, Funda Meric‐Bernstam, Christopher J. Sweeney, Razelle Kurzrock, Howard A. Burris III, David R. Spigel, Hanna Tukachinsky, Jason Hughes, Julia Malato, Bongin Yoo, Tania Szado, Cheryl Schwab, Lincoln W. Pasquina, Amaya Gasco, Katja Schulze, Claire F. Friedman   +17 more
wiley   +1 more source