Results 131 to 140 of about 7,668,561 (373)

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Population genetics: An introduction for physicists

SciPost Physics Lecture Notes
Population genetics lies at the heart of evolutionary theory. This topic forms part of many biological science curricula but is rarely taught to physics students.
Andrea Iglesias-Ramas, Samuele Pio Lipani, Rosalind J. Allen
doaj   +1 more source

Population genetics provides new insights into biomarker prevalence in dab (Limanda limanda L.): a key marine biomonitoring species [PDF]

, 2013
Niklas Tysklind, Martin I. Taylor, Brett P. Lyons, Freya Goodsir, Ian McCarthy, Gary R. Carvalho   +5 more
openalex   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Polygenic scores for longitudinal prediction of incident type 2 diabetes in an ancestrally and medically diverse primary care physician network: a patient cohort study

Genome Medicine
Background The clinical utility of genetic information for type 2 diabetes (T2D) prediction with polygenic scores (PGS) in ancestrally diverse, real-world US healthcare systems is unclear, especially for those at low clinical phenotypic risk for T2D ...
Ravi Mandla, Philip Schroeder, Bianca Porneala, Jose C. Florez, James B. Meigs, Josep M. Mercader, Aaron Leong   +6 more
doaj   +1 more source

Conditioning the logistic branching process on non-extinction

, 2013
We consider a birth and death process in which death is due to both `natural death' and to competition between individuals, modelled as a quadratic function of population size.
Etheridge, Alison, Wang, Shidong, Yu, Feng   +2 more
core  

European Code Against Cancer, 5th edition – hormone replacement therapy, other common medical therapies and cancer

Molecular Oncology, EarlyView.
The 5th edition of the European Code Against Cancer (ECAC5) contains 14 recommendations on cancer prevention. Here, we update the cancer prevention recommendations regarding the use of hormone replacement therapy (HRT), which is positioned as recommendation number 13 of the ECAC5.
Mangesh A. Thorat, Marc Arbyn, David Baldwin, Xavier Castells, Solveig Hofvind, Urska Ivanus, Carlo Senore, Esther Toes‐Zoutendijk, Carlijn van der Aalst, Carlos Canelo‐Aybar, Fiorella Karina Fernández‐Sáenz, Ariadna Feliu, Hajo Zeeb, Andre L. Carvalho, Erica D'Souza, David Ritchie, Carolina Espina, Iris Lansdorp‐Vogelaar, Andrea DeCensi   +18 more
wiley   +1 more source

Implications of fisheries during the spawning season for the sustainable management and recovery of depleted fish stocks: a conceptual framework [PDF]

, 2009
Fishing during the spawning season may negatively affects the reproductive potential and reproductive dynamics of exploited fish stocks due to a variety of mechanisms such as the disturbance of the natural spawning behaviour, effects on the age, size and
Rijnsdorp, A.D.
core   +1 more source

BURROWING OWL (ATHENE CUNICULARIA) POPULATION GENETICS: A COMPARISON OF NORTH AMERICAN FORMS AND MIGRATORY HABITS [PDF]

, 2005
Nicole M. Korfanta, David B. McDonald, Travis C. Glenn   +2 more
openalex   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source