Results 201 to 210 of about 7,398,608 (386)

Population Genetics in the Human Microbiome.

open access: yesTrends in Genetics, 2019
Nandita R. Garud, K. Pollard
semanticscholar   +1 more source

Evaluation and modification of tumor cell isolation techniques from malignant effusions for rapid drug sensitivity testing

open access: yesMolecular Oncology, EarlyView.
Non‐small cell lung cancer targeted treatment is limited to a few known genetic alterations, with few alternatives in advanced treatment lines. To direct treatment decisions by drug sensitivity testing (DST), this study compared several methods for tumor cell isolation from malignant effusions, pointing to repeated CD45+ cell depletion for effective ...
Navit Mooshayef   +10 more
wiley   +1 more source

Population Genetics Meets Ecology: A Guide to Individual-Based Simulations in Continuous Landscapes. [PDF]

open access: yesEcol Evol
Chevy ET   +11 more
europepmc   +1 more source

Beyond cytotoxic T cells: reprogrammed regulatory T cells help facilitate response to dual checkpoint blockade

open access: yesMolecular Oncology, EarlyView.
Rolig, Peng, and colleagues have shed new light on how dual blockade of PD1 and LAG3 enhances antitumor immunity. They found that response to immunotherapy with anti‐PD1 + anti‐LAG3 was associated with reprogramming of canonically suppressive CD4+ regulatory T cells to an inflammatory state.
Tullia C. Bruno, Anthony R. Cillo
wiley   +1 more source

K-mer-based Approaches to Bridging Pangenomics and Population Genetics. [PDF]

open access: yesMol Biol Evol
Roberts MD   +3 more
europepmc   +1 more source

Population Genetics of Mexican Drosophila: I. Chromosomal variation in natural populations of Drosophila pseudoobscura from Central Mexico [PDF]

open access: green, 1975
Th. Dobzhansky   +7 more
openalex   +1 more source

Understanding and measuring mechanical signals in the tumor stroma

open access: yesFEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz   +3 more
wiley   +1 more source

Population Genetics of Atlantic Salmon (<i>Salmo salar</i>) in Prince Edward Island, Canada. [PDF]

open access: yesEcol Evol
Grove CM   +6 more
europepmc   +1 more source

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