Results 201 to 210 of about 1,325,954 (330)

Mitochondria‐associated membranes (MAMs): molecular organization, cellular functions, and their role in health and disease

FEBS Open Bio, EarlyView.
Mitochondria‐associated membranes (MAMs) are contact sites between the endoplasmic reticulum and mitochondria that regulate calcium signaling, lipid metabolism, autophagy, and stress responses. This review outlines their molecular organization, roles in cellular homeostasis, and how dysfunction drives neurodegeneration, metabolic disease, cancer, and ...
Viet Bui, Maryline Santerre, Natalia Shcherbik, Bassel E Sawaya   +3 more
wiley   +1 more source

Pilot study on the population genetics structure of <i>Fasciola hepatica</i> from seven provinces of South Africa. [PDF]

Front Vet Sci
Nukeri S, Malatji MP, Mnisi CM, Chaisi M, Mukaratirwa S.   +4 more
europepmc   +1 more source

Population Genetics in the American Tropics. X. Genetic Load Differences in Drosophila willistoni from Colombia [PDF]

, 1977
H. F. Hoenigsberg, J. J. Palomino, M. J. Hayes, I. Z. Zandstra, Guadalupe Rojas   +4 more
openalex   +1 more source

Interplay between RNA‐protein interactions and RNA structures in gene regulation

FEBS Open Bio, EarlyView.
Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko, Mauro Scaravilli, Minna‐Liisa Änkö   +2 more
wiley   +1 more source

Population Genetics Meets Ecology: A Guide to Individual-Based Simulations in Continuous Landscapes. [PDF]

Ecol Evol
Chevy ET, Min J, Caudill V, Champer SE, Haller BC, Rehmann CT, Smith CCR, Tittes S, Messer PW, Kern AD, Ramachandran S, Ralph PL.   +11 more
europepmc   +1 more source

The population genetics of Duchenne: natural and artificial selection in Duchenne muscular dystrophy. [PDF]

, 1986
James Edwards
openalex   +1 more source

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

FEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee, Jung Yoon Ho, In Sun Hwang, Youn Jin Choi   +3 more
wiley   +1 more source

Bacterial Population Genetics in Infectious Disease

Emerging Infectious Diseases, 2011
Didier Raoult
doaj   +1 more source

K-mer-based Approaches to Bridging Pangenomics and Population Genetics. [PDF]

Mol Biol Evol
Roberts MD, Davis O, Josephs EB, Williamson RJ.   +3 more
europepmc   +1 more source

HSP70 governs permeability and mechanotransduction in primary human endothelial cells

FEBS Open Bio, EarlyView.
HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez, Everton G. Melo, Isadora C. B. Pavan, Percíllia V. S. Oliveira, Luiza B. C. T. Coimbra, Thaís L. S. Araujo   +5 more
wiley   +1 more source