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Genetics of population isolates
Clinical Genetics, 2002Genetic isolates, as shown empirically by the Finnish, Old Order Amish, Hutterites, Sardinian and Jewish communities among others, represent a most important and powerful tool in genetically mapping inherited disorders. The main features associated with that genetic power are the existence of multigenerational pedigrees which are mostly descended from ...
Mauricio Arcos-Burgos, Maximilian Muenke
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Genetic Inheritance and Population Genetics
2008Variation in DNA sequence produces genetic polymorphisms (Greek: many forms). A polymorphism is any DNA sequence in which the less common allele occurs at a frequency of 1% or greater. The first polymorphisms that were identified were those defining the serologic blood groups.
Daniel L. Koller, Tatiana Foroud
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Introduction to Quantitative Genetics
Quantitative Genetics, 2012So far in this course we have dealt entirely either with the evolution of characters that are controlled by simple Mendelian inheritance at a single locus or with the evolution of molecular sequences.
G. Acquaah
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2005
The aim of fish breeding is not to change individual fish, but rather the fish population. Thus, our knowledge about Mendelian inheritance must be extended from the level of the individual to the level of the population. Population genetics may be defined as the study of Mendelian genetics in a group of interbreeding individuals who share a common gene
Andersen, Oivind, Hayes, Ben
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The aim of fish breeding is not to change individual fish, but rather the fish population. Thus, our knowledge about Mendelian inheritance must be extended from the level of the individual to the level of the population. Population genetics may be defined as the study of Mendelian genetics in a group of interbreeding individuals who share a common gene
Andersen, Oivind, Hayes, Ben
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Population genetics of phenylketonuria
Acta Paediatrica, 1994Phenylketonuria (PKU) is an autosomal recessive disorder caused by a large number of mutations at the phenylalanine hydroxylase (PAH) locus, most of which are strongly associated with specific RFLP or VNTR haplotypes. One of the major questions remaining in PKU research is why this apparently maladaptive disorder has been maintained at a frequency of ...
Slc Woo, RC Eisensmith
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Journal of Helminthology, 1998
Population genetics seeks to understand the genetic relationships within and between populations of a species and the processes that generate these patterns. Little is known about the population genetics of parasitic nematodes. This is a notable gap in our knowledge since understanding the population genetic patterns and processes of parasitic ...
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Population genetics seeks to understand the genetic relationships within and between populations of a species and the processes that generate these patterns. Little is known about the population genetics of parasitic nematodes. This is a notable gap in our knowledge since understanding the population genetic patterns and processes of parasitic ...
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Current Opinion in Plant Biology, 2002
Molecular population genetics is entering a new era dominated by studies of genomic polymorphism. Some of the theory that will be needed to analyze data generated by such studies is already available, but much more work is needed. Furthermore, population genetics is becoming increasingly relevant to other fields of biology, for example to genetic ...
Hideki Innan, Magnus Nordborg
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Molecular population genetics is entering a new era dominated by studies of genomic polymorphism. Some of the theory that will be needed to analyze data generated by such studies is already available, but much more work is needed. Furthermore, population genetics is becoming increasingly relevant to other fields of biology, for example to genetic ...
Hideki Innan, Magnus Nordborg
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THE GENETICAL STRUCTURE OF POPULATIONS
Annals of Eugenics, 1949The articles published by the Annals of Eugenics (1925–1954) have been made available online as an historical archive intended for scholarly use. The work of eugenicists was often pervaded by prejudice against racial, ethnic and disabled groups. The online publication of this material for scholarly research purposes is not an endorsement of those views
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The population genetics of anisogamy
Journal of Theoretical Biology, 1978Abstract This paper analyses the population genetics of anisogamy controlled by a single locus, in both the haploid and diploid cases. The conclusions of Parker et al. (1972), based on computer calculations, are confirmed analytically. The effects of the existence of two mating types on the evolution of anisogamy are examined. Close linkage between a
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