Results 81 to 90 of about 1,354,014 (293)

Improved allele frequencies in gnomAD through local ancestry inference

Nature Communications
The Genome Aggregation Database (gnomAD) is a foundational resource for allele frequency data, widely used in genomic research and clinical interpretation.
Pragati Kore, Michael W. Wilson, Grace Tiao, Katherine Chao, Philip W. Darnowsky, Nicholas A. Watts, Jessica Honorato Mauer, Samantha M. Baxter, Genome Aggregation Database Consortium, Heidi L. Rehm, Mark J. Daly, Konrad J. Karczewski, Elizabeth G. Atkinson   +12 more
doaj   +1 more source

Model inspired by population genetics to study fragmentation of brittle plates

, 2007
We use a model whose rules were inspired by population genetics, the random capability growth model, to describe the statistical details observed in experiments of fragmentation of brittle platelike objects, and in particular the existence of (i ...
de Oliveira, Viviane M., Gomes, M. A. F.
core   +1 more source

Assessing Cognitive Functioning in Children With Brain Tumors: Interaction of Neighborhood Social Determinants of Health and Neurological Risk

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background This study investigated how neighborhood‐level social determinants of health (SDOH), including redlining and neurological risk, interact to influence cognitive outcomes in children treated for brain tumors (CTBT). Methods A retrospective chart review of 161 CTBT aged 5–17 was conducted.
Alannah R. Srsich, Manali Zope, Peter M. Fantozzi, Cassie N. Kline, Iris Paltin, Matthew C. Hocking   +5 more
wiley   +1 more source

Efficient Forward Simulation of Fisher-Wright Populations with Stochastic Population Size and Neutral Single Step Mutations in Haplotypes

, 2012
In both population genetics and forensic genetics it is important to know how haplotypes are distributed in a population. Simulation of population dynamics helps facilitating research on the distribution of haplotypes.
Andersen, Mikkel Meyer, Eriksen, Poul Svante   +1 more
core  

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Genetic Sex and Origin Identification Suggests Differential Migration of Male and Female Atlantic Bluefin Tuna (Thunnus thynnus) in the Northeast Atlantic

Evolutionary Applications
Knowledge about sex‐specific difference in life‐history traits—like growth, mortality, or behavior—is of key importance for management and conservation as these parameters are essential for predictive modeling of population sustainability.
Einar Eg Nielsen, Kim Birnie‐Gauvin, Henrik Baktoft, Haritz Arrizabalaga, Tomas Brodin, Massimiliano Cardinale, Michele Casini, Gustav Helström, Teunis Jansen, Anders Koed, Petter Lundberg, Brian R. MacKenzie, Antonio Medina, Søren Post, Naiara Rodriguez‐Ezpeleta, Andreas Sundelöf, José Luis Varela, Kim Aarestrup   +17 more
doaj   +1 more source

A Multivariate Moran Process with Lotka-Volterra Phenomenology

, 2011
For a population with any given number of types, we construct a new multivariate Moran process with frequency-dependent selection and establish, analytically, a correspondence to equilibrium Lotka-Volterra phenomenology.
Fagan, William F., Hastings, Alan, Noble, Andrew E.   +2 more
core   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Adaptive non-uniform mutation based on statistics for genetic algorithms [PDF]

, 2002
Copyright @ 2002 ACMAs a meta-heuristic search algorithm based on mechanisms abstracted from population genetics, the genetic algorithm (GA) implicitly maintains the statistics about the search space through the population.
Yang, S
core  

Utterance Selection Model of Language Change

, 2005
We present a mathematical formulation of a theory of language change. The theory is evolutionary in nature and has close analogies with theories of population genetics. The mathematical structure we construct similarly has correspondences with the Fisher-
A. J. McKane, C. W. Gardiner, D. L. Hull, D. L. Hull, E. Gordon, G. J. Baxter, H. Risken, J. A. Hawkins, J. F. Crow, J. L. Bybee, J. Ohala, J. Pierrehumbert, L. Milroy, M. H. Christiansen, M. Kimura, M. Kimura, M. Tomasello, N. Takahata, P. Niyogi, P. Trudgill, R. A. Blythe, R. A. Fisher, R. Bürger, R. Keller, S. S. Mufwene, S. Wright, W. Croft, W. Croft, W. Croft, W. Labov, W. Labov   +30 more
core   +1 more source