Results 121 to 130 of about 5,275,751 (292)
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Growth in a cross-section of cities: location, increasing returns or random growth? [PDF]
This article analyzes empirically the main existing theories on income and population city growth: increasing returns to scale, locational fundamentals and random growth.
Jose Olmo, Rafael González-Val
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Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
R&D-Based Growth in the Post-Modern Era. [PDF]
Conventional R&D-based growth theory suggests that productivity growth is positively correlated with population size or population growth, an implication which is hard to see in the data.
Alexia Prskawetz +2 more
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Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
The eco-social problems of the Bangladesh’ republic development
RUDN Journal of Ecology and Life Safety, 2013 Article is devoted what socially to country development. Difficulties, which faced the republic of Bangladesh on the way of the development, are shown. Some statistical data on the basic ecological and to socio-economic indexes of development of a state ...
- Alam Md Shamsher
doaj
Developing country growth collapse revisited: demographic influences and regional differences [PDF]
This paper bridges two related, but up to now, unconnected literatures: economic growth stability and population-economic growth. The paper is different from previous population-economic growth analyses by focusing on instability of economic growth in ...
Brantley Liddle
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Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Association between economic growth and early childhood nutrition – Authors' reply
The Lancet Global Health, 2015 Sebastian Vollmer +5 more
doaj +1 more source
Constant Savings Rates and Quasi-Arithmetic Population Growth under Exhaustible Resource Constraints [PDF]
In the Dasgupta-Heal-Solow-Stiglitz model of capital accumulation and resource depletion we show the following equivalence: If an efficient path has constant (gross and net of population growth) savings rates, then population growth must be quasi ...
Cees A. Withagen +4 more
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