Results 161 to 170 of about 2,072,147 (313)

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Beyond Temperature: Relative Humidity Systematically Shifts Juvenile Thermal Performance and Projected Population Growth in a Malaria Vector. [PDF]

Ecol Lett
Huxley PJ, Brown JJ, St Laurent B, Johnson B, Cheung OY, Asamoah A, Hollingsworth BD, Bump ER, Wimberly MC, Pascual M, Johnson LR, Murdock CC.   +11 more
europepmc   +1 more source

Demographic change and transport needs in the Waikato region

, 2005
This report has been commissioned by Environment Waikato (EW) as part of its review of the Land Transport Strategy for the Waikato region. The report identifies key population characteristics that impact on transport needs of the EW region and the ...
Baxendine, Sandra, Poot, Jacques, Cochrane, William   +2 more
core  

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Thermal performance of <i>Wolffia globosa</i> under climate change: heatwaves impair population growth. [PDF]

AoB Plants
Cuddington K, Kuntze M, Andrade-Pereira D, Gasmen Y, Wu J, Ferns A, Geng X.   +6 more
europepmc   +1 more source

Migration, urban population growth and regional disparity in China [PDF]

The main objective of this paper is to study the determinants of city population growth in China during the 1990s', as well as the determinants of migrations towards cities, which constitutes the main source of urban population growth in this period.
Mary-Françoise Renard, Zelai Xu, Nong Zhu   +2 more
core  

Why human connection is the true metric of research success

FEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan, Mattias Wei Ren Kon, Xavier Coumoul, Fun Man Fung   +3 more
wiley   +1 more source

Forecasting the impact of Kazakhstan population growth on healthcare doctors demand. [PDF]

BMC Health Serv Res
Koichubekov B, Begaidarova R, Omarbekova N, Mukhanova M, Abdikadirova K, Kharin A, Omarkulov B.   +6 more
europepmc   +1 more source

Population Aging and Economic Growth: the effect of health expenditure [PDF]

Rising longevity has led to population aging in developed countries, causing increasing concerns about its economic impact. Specially, the trend of population aging increases health expenditure in developed countries, and 70% to 80% of health expenditure
Atsue Mizushima
core  

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source