Results 71 to 80 of about 1,587,313 (317)

Response to neoadjuvant chemotherapy in early breast cancers is associated with epithelial–mesenchymal transition and tumor‐infiltrating lymphocytes

open access: yesMolecular Oncology, EarlyView.
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane   +16 more
wiley   +1 more source

A Regional Perspective on Urbanization and Climate-Related Disasters in the Northern Coastal Region of Central Java, Indonesia

open access: yesLand, 2018
Indonesia, as an archipelagic nation, has about 150 million people (60%) living in coastal areas. Such communities are increasingly vulnerable to the effects of change, in the form of sea level rise and stronger, more intense storms. Population growth in
Iwan Rudiarto   +2 more
doaj   +1 more source

Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression

open access: yesMolecular Oncology, EarlyView.
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park   +6 more
wiley   +1 more source

Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi   +26 more
wiley   +1 more source

Population growth parameters of Tetranychus urticae (Acari: Tetranychidae) on different bean varieties [PDF]

open access: yesنامه انجمن حشره‌شناسی ایران, 2007
Population growth parameters of Tetranychus urticae Koch on four bean varieties including Talash (Colorado bean), Sadaf (Navy bean), Goli (Kidney bean) and Parastoo (Black-eye bean) were investigated in laboratory conditions at 25 ± 1°C, 60 ± 5% RH ...
M. Ahmadi, Y. Fathipour, K. Kamali
doaj  

Dar es Salaam city temporal growth and its influence on transportation

open access: yesUrban, Planning and Transport Research, 2014
This study aims at using spatial data to investigate and analyze the temporal spatial growth of the city of Dar es Salaam in Tanzania and quantify its relationship to transportation growth.
Charles Cosmas Mkalawa, Pan Haixiao
doaj   +1 more source

GDP Growth Rate and Population [PDF]

open access: yesSSRN Electronic Journal, 2006
Real GDP growth rate in developed countries is found to be a sum of two terms. The first term is the reciprocal value of the duration of the period of mean income growth with work experience, Tcr. The current value of Tcr in the USA is 40 years. The second term is inherently related to population and defined by the relative change in the number of ...
openaire   +5 more sources

TOMM20 as a driver of cancer aggressiveness via oxidative phosphorylation, maintenance of a reduced state, and resistance to apoptosis

open access: yesMolecular Oncology, EarlyView.
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam   +9 more
wiley   +1 more source

Le vieillissement démographique des communes côtières en France : un phénomène uniforme ?

open access: yesEspace populations sociétés, 2013
There are many articles about ageing but few on the intensity of the phenomenon on the coast. Having specified the geographical limits and the methodology of the analysis, the article reveals the geographical variation of the phenomenon.
Jean-François Ghekière   +1 more
doaj   +1 more source

Elucidating prognostic significance of purine metabolism in colorectal cancer through integrating data from transcriptomic, immunohistochemical, and single‐cell RNA sequencing analysis

open access: yesMolecular Oncology, EarlyView.
Low expression of five purine metabolism‐related genes (ADSL, APRT, ADCY3, NME3, NME6) was correlated with poor survival in colorectal cancer. Immunohistochemistry analysis showed that low NME3 (early stage) and low ADSL/NME6 (late stage) levels were associated with high risk.
Sungyeon Kim   +8 more
wiley   +1 more source

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