Results 71 to 80 of about 5,275,751 (292)

Estimating population attributable risk fraction of determinants of pediatric obesity

open access: yesBMC Public Health
Objectives Childhood obesity imposes a remarkable socio-economic and health-related burden, with an increasing worldwide trend. We aimed to assess the relationship between modifiable factors and obesity in Iranian children and adolescents along with to ...
Maryam Yazdi   +6 more
doaj   +1 more source

Population Genetics and Economic Growth [PDF]

open access: yes
This paper builds an age-structural model of human population genetics in which agents are endowed with a high-dimensional genome that determines their cognitive and physical characteristics. Young adults optimally search for a marriage partner, work for
Kwang Woo Park, Paul J. Zak
core  

Population Growth and Decline in City Neighborhoods [PDF]

open access: yes, 2002
Analyzes how neighborhoods in the nation's largest cities grew and declined in the 1990s and how those results compared with patterns of change in the 1980s, based on data from the U.S.
G. Thomas Kingsley, Kathryn L. S. Pettit
core  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Grow or die: A 49‐year growth history of a Japanese warm‐temperate tree species

open access: yesEcosphere
The growth trajectories of trees are not fully understood due to their long life span. We characterized the population dynamics of the canopy tree Castanopsis cuspidata (Thunb.) Schottky in a Japanese warm‐temperate forest over 49 years (1966–2015).
Toshihiro Yamada   +12 more
doaj   +1 more source

Sustaining life: Protecting Pakistan’s fertile soil and advocating against soil sealing

open access: yesJournal of Agriculture, Food Systems, and Community Development
Introduction Pakistan is facing a growing crisis as rapid popula­tion expansion and shrinking fertile land put im­mense pressure on food production. One of the most alarming threats to agriculture is soil sealing—the process of covering fertile land ...
Amanullah
doaj   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

Land-use land cover changes and their relationship with population and climate in Western Uganda

open access: yesJournal of Degraded and Mining Lands Management
Sustainable management of land and its ecosystem requires well-documented Land-use and Land Cover changes (LULCCs) that have occurred over time. The objective of this study was to document the LULCCs, determine their relationship with climate and ...
Noel Kishaija   +2 more
doaj   +1 more source

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