Results 101 to 110 of about 19,619,693 (258)
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
BMC NephrologyBackground Evidence on inequities in long-term chronic kidney disease (CKD) outcomes from population-based cohorts is limited, and geographic inequities across the full spectrum of CKD in Australia remain under-examined.
Jasmine K. H. Sidhu +11 more
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Webinar—Applying Global Goods: Community Health Guidelines, Measurement and Planning Tools
, 2021 This webinar aims to provide guidance and harmonization of how to approach and pragmatically implement various global guidelines, planning and measurement tools in community health so they can be readily used in alignment with national priorities.
Population Council +1 more
core +1 more source
BMC Health Services ResearchBackground The goal of the Integrated Access to Cancer Screening (IACS) initiative was to help reduce the disparity in cancer screening participation across Alberta by implementing an integrated mobile service delivery model for breast, cervical, and ...
Jessica Wiseman +9 more
doaj +1 more source
Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
Validation of ukpds outcomes and Taiwan diabetes models on Taiwan type 2 dm population
, 2020 [[abstract]]Asians with predisposition for diabetes mellitus (DM) contributed to over 60% of the world’s diabetic population. DM model has been widely applied in assisting healthcare decision.
Lin, MY;Huang, TY;Liu, JS;Hsu, CC;Kang, Y;Hwang, SJ;Luh, H
core +1 more source
Painting a portrait: Analysis of national health survey data for cancer genetic counseling
Cancer Medicine, 2019 Background Despite a growing body of literature describing the geographic and sociodemographic distribution of cancer genetic testing, work focused on these domains in cancer genetic counseling is limited.
Monica H. Stamp +3 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Summer Seminar on Population (38th : 2007 : Honolulu, Hawaii)
, 2007 For more about the East-West Center, see https://www.eastwestcenter.org/The 2007 Summer Seminar on Population will consist of three workshops.Workshop 1: Population, development, and policy: the economic payoffs of population changeWorkshop 2: Livable ...
East-West Center. Population and Health Studies
core +1 more source