Results 131 to 140 of about 4,760,541 (315)

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Nepal Inequalities in Health, Nutrition, and Population

, 2003
This paper focuses on the inequalities in health, nutrition, and population in Nepal. It presents data on disaggregated health status and health services utilization that is organized by asset or wealth quintiles,
Ritu Cchabra, Deborah Vazirani, Elizabeth Lule, Lule, Elizabeth, Nandini Oomman, Cchabra, Ritu, Vazirani, Deborah, Oomman, Nandini   +7 more
core   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Summer Seminar on Population (33rd : 2002 : Honolulu, Hawaii)

, 2002
For more about the East-West Center, see https://www.eastwestcenter.org/The 2002 Summer Seminar on Population will consist of three workshops.Workshop 1: Analyzing adolescent risk-taking behavior and evaluating intervention programsWorkshop 2: Using HIV ...
East-West Center. Population and Health Studies
core  

Turkey Inequalities in Health, Nutrition and Population

, 2003
This paper focuses on the inequalities in health, nutrition, and population in Turkey. It presents data on disaggregated health status and health services utilization that is organized by asset or wealth quintiles,
Ritu Chhabra, Elizabeth Lule, Lule, Elizabeth, Nandini Oomman, Chhabra, Ritu, Oomman, Nandini   +5 more
core   +1 more source

Seasonality in Cough: The Influence of Environmental Physiology

Laryngoscope Investigative Otolaryngology
Background/Objectives Cough is a prevalent clinical problem associated with comorbidities and environmental conditions. We seek to highlight the clinically measurable impact of the environment on cough physiology by modeling the incidence and prevalence ...
Michelle Pistner Nixon, Anas Qatanani, Amanda J. Young, Mudit Gupta, Kenneth W. Altman   +4 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Niger Inequalities in Health, Nutrition and Population

, 2003
This paper focuses on the inequalities in health, nutrition, and population in Niger. It presents data on disaggregated health status and health services utilization that is organized by asset or wealth quintiles,
Deborah Vazirani, Ritu Chhabra, Elizabeth Lule, Lule, Elizabeth, Nandini Oomman, Chhabra, Ritu, Vazirani, Deborah, Oomman, Nandini   +7 more
core   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Malawi Inequalities in Health, Nutrition and Population

, 2003
This paper focuses on the inequalities in health, nutrition, and population in Malawi. It presents data on disaggregated health status and health services utilization that is organized by asset or wealth quintiles,
Deborah Vazirani, Ritu Chhabra, Elizabeth Lule, Lule, Elizabeth, Nandini Oomman, Chhabra, Ritu, Vazirani, Deborah, Oomman, Nandini   +7 more
core   +1 more source