Results 211 to 220 of about 5,029,790 (262)

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

FEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman, Katarzyna Stapor, Leszek Konieczny, Krzysztof Gądek, Piotr Nowakowski   +4 more
wiley   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

Development of human monoclonal antibodies against TARM1 by yeast display

FEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe, Mayumi Saeki, Masaaki Hashiguchi, Sayaka Ono, Kazuhisa Aoki, Hidetaka Tanno   +5 more
wiley   +1 more source

Population Health Imperiled

The Milbank Quarterly
openaire   +2 more sources

Reaching the highest efficiency: The need for a balance of ethical and financial incentives - population-based financing in integrated networks in Germany

International Journal of Integrated Care, 2013
Helmut Hildebrandt
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Blockchain and population health

Journal of Public Health, 2022
Abstract Background Blockchain technology has made great strides in many industries but has yet to impact the world of public health. Population health issues such as outbreak surveillance and controlled substance tracking during emergencies all require a secure, easily accessible database.
Mark, Gaynor, Rhonda, BeLue, J E, Tuttle-Newhall, Maxwell, Martin, Frank, Patejdl, Clare, Vogt   +5 more
openaire   +2 more sources

The Politics of Population Health

The Milbank Quarterly, 2023
Policy Points Despite increased spending and consuming more health care services than any other country in the world, the United States global health rankings experience continued decline, including worsening performance in life expectancy and mortality owing to lack of investment in and strategies on the upstream determinants of health.
Daniel, Dawes, Juan, Gonzalez
openaire   +2 more sources

Health and Population

Foreign Affairs, 1965
The demographic interactions of health programs family planning economic development and population growth are discussed. Generally with social modernization a decline in birthrates follows a decline in mortality rates. Basic medical care alleviates immediate suffering while preventive health services contribute to long-term economic development by ...
openaire   +2 more sources

Promoting the health of the population

BMJ, 2014
The BMA is right to urge a prospective government to prioritise public health.1 Urgent action is needed in key areas including smoking, obesity, and mental health. However, individual topics should not be promoted in isolation.2 What we need is a long term strategic approach that also confronts the ubiquitous problem of inequalities.
Michael C, Watson, John, Lloyd
openaire   +2 more sources

Population ageing and health

The Lancet, 2012
www.thelancet.com Vol 379 April 7, 2012 1295 Submissions should be made via our electronic submission system at http://ees.elsevier.com/ thelancet/ agenda, there are worrying signs of discrimination against older people. Background documents from the UN High-Level Meeting in September, 2010, describe the deaths of people younger than 60 or 70 years as “
Lloyd-Sherlock, Peter, McKee, Martin, Ebrahim, Shah, Gorman, Mark, Greengross, Sally, Prince, Martin, Pruchno, Rachel, Gutman, Gloria, Kirkwood, Tom, O'Neill, Desmond, Ferrucci, Luigi, Kritchevsky, Stephen B., Vellas, Bruno   +12 more
openaire   +3 more sources