Results 251 to 260 of about 18,274,837 (361)

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Beyond the Demographic and Health Survey: on the past and future of population health surveillance. [PDF]

BMJ Glob Health
Nott J, Kaunda-Khangamwa B, Mathanga DP, Molenaar J, Taithe B, Phiri C, Chintsanya J, Munthali A.   +7 more
europepmc   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Imagining Genomics and Population Health in 2050: Anticipating Future Research, Policy, and Governance Needs.

Public Health Genomics
Knoppers BM, Joly Y, Zawati MANH, Alsafar H, Barrett JC, Blackburn L, Chung BH, Cornel MC, Dove ES, Glazer D, Ho CW, Khoury MJ, Lewis ACF, Lucassen A, Mills PFR, Mitchell C, Mulder N, Newson AJ, Ng A, Pharoah PDP, Rahimzadeh V, Roberts MC, Sanderson SC, Skopek JM, Zimmern R, Meslin EM.   +25 more
europepmc   +1 more source

Seasonal migration and healthy ageing in China: protocol for the Frigid-Tropical Migratory Population Health (ftMPH) cohort. [PDF]

BMJ Open
Guo J, Tian J, Han Y, Yan S, Jin C, Chang X, Wu X, Song W, Wang F, Zhang B, Ji Y.   +10 more
europepmc   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Community-oriented primary care: The missing link

African Journal of Primary Health Care & Family Medicine, 2010
Steve Reid
doaj   +1 more source

Research on China's population health policy: an analysis based on the PMC index model. [PDF]

BMC Public Health
Cai R, Shen C, Wang X, Zhao S, Zhang T.
europepmc   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source

Recurrent climate related extreme events and patterns of race/ethnic mortality: opportunities to advance population health equity. [PDF]

J Clim Chang Health
Daley DM, Swenson MH, Saint Onge JM.
europepmc   +1 more source