Total hip arthroplasty restores population health-related quality of life norms : a propensity-matched study with mediation analysis of BMI. [PDF]
Ablett AD +3 more
europepmc +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
OnabotulinumtoxinA Treatment for Masseter Muscle Prominence: 6-Month Safety and Efficacy Results, Including Patient-Reported Outcomes, From a Phase 3, Randomized, Placebo-Controlled, Multiregional Trial. [PDF]
Sun J +15 more
europepmc +1 more source
Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source
Sparse testcrossing for early-stage genomic prediction of general combining ability to increase genetic gain in maize hybrid breeding programs. [PDF]
González-Diéguez DO +5 more
europepmc +1 more source
Efficacy and Tolerability of Viloxazine Extended-Release for Attention-Deficit/Hyperactivity Disorder in Adolescents and Adults: A Systematic Review With Qualitative Synthesis of All Studies and Meta-Analysis of Adolescent Data. [PDF]
Chapman SR +3 more
europepmc +1 more source
Counting what matters: stillbirth estimates before 28 weeks of gestation in India. [PDF]
Tikmani SS, Saleem S.
europepmc +1 more source
From Efficacy to Effectiveness: When Proven Therapies Fail. [PDF]
McClintick D, Cheng S, Ebinger JE.
europepmc +1 more source

