Results 51 to 60 of about 2,095,765 (308)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Demographic change and transport needs in the Waikato region [PDF]

open access: yes, 2005
This report has been commissioned by Environment Waikato (EW) as part of its review of the Land Transport Strategy for the Waikato region. The report identifies key population characteristics that impact on transport needs of the EW region and the ...
Baxendine, Sandra   +2 more
core  

1980 census of population. [PDF]

open access: yes, 1982
"PC80-1-B36."Includes index."Issued August 1982.""Population Division"--T.p.
United States. Bureau of the Census. Population Division
core   +4 more sources

Index of Orthodontic Treatment Need in Referred Nepalese Population

open access: yesOrthodontic Journal of Nepal, 2012
Objective: The study aims to assess the need for orthodontic treatment in a group of referred Nepalese population of Kathmandu valley. Materials & Method: Dental Health Component (DHC) and Aesthetic Component (AC) of the Index of Orthodontic ...
Sujita Shrestha, Rabindra Man Shrestha
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

The prevalence of malocclusion in Maltese schoolchildren as measured by the Index of Orthodontic Treatment Need [PDF]

open access: yes, 2007
The Index of Orthodontic Treatment Need (IOTN), a widelyused, standardised epidemiological tool was used to determine the prevalence of malocclusion in Maltese schoolchildren.
Mulligan, Kevin M., Camilleri, Simon
core  

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Hurricane Loss Analysis Based on the Population-Weighted Index

open access: yesFrontiers in Built Environment, 2017
This paper discusses different measures for quantifying regional hurricane loss. The main measures used in the past are normalized percentage loss and dollar value loss.
Grzegorz Kakareko   +5 more
doaj   +1 more source

Cardio-Ankle Vascular Index in a Thai Population [PDF]

open access: yesPulse, 2016
Arterial stiffness as measured by the cardio-ankle vascular index (CAVI) is a widely available method in Thailand. Data from a large cross-sectional study revealed a significant correlation of CAVI and the presence of coronary artery disease as detected from 64-slice coronary computed tomography arteriography. Futhermore, CAVI was shown to predict long-
Teerapat, Yingchoncharoen   +1 more
openaire   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

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