Results 101 to 110 of about 513,538 (268)
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Exploring the diversity of three Northern Atlantic sea beet populations
Frontiers in Plant ScienceSea beet [Beta vulgaris ssp. maritima (L.) Arcang.] populations exhibit high genetic diversity and possess valuable traits that could enhance resilience, disease resistance, and tolerance to abiotic stress. In contrast, the genetic variation in the sugar
Lisa Bertram +4 more
doaj +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
National population mapping from sparse survey data: A hierarchical Bayesian modeling framework to account for uncertainty. [PDF]
Proc Natl Acad Sci U S A, 2020 Leasure DR +4 more
europepmc +1 more source
Artificial molecular machines and motors—Design and control of nanoscale motion
FEBS Letters, EarlyView.Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
The ubiquitin system in normal and infected germinal center B cells
FEBS Letters, EarlyView.The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source
Genetic mapping of Ascochyta blight resistance in an ILL6002 × Indianhead lentil mapping population
The Plant GenomeAscochyta blight of lentil (Lens culinaris Medik.) is a fungal disease caused by Ascochyta lentis. This study was carried out to identify the location of quantitative trait loci (QTL) associated with resistance from the accession Indianhead, and how ...
Em L. Thackwray +5 more
doaj +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Measuring the contribution of built-settlement data to global population mapping.
Soc Sci Humanit Open, 2021 Nieves JJ +10 more
europepmc +1 more source