Results 91 to 100 of about 7,589,489 (318)
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Neutrosophic Exponential Ratio-Type Estimator for Finite Population Mean in Stratified Sampling [PDF]
Neutrosophic Sets and SystemsThis paper introduces an innovative neutrosophic exponential ratio-type estimator for estimating finite population means in stratified sampling environments with indeterminate data.
Anisha Taneja +2 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Composite Estimators for the Population Mean Under Ranked Set Sampling
MathematicsRanked Set Sampling (RSS) is an effective sampling technique, particularly when precise measurement of the study variable is costly or time-consuming, but ranking the units is relatively easy.
Sayed A. Mostafa +2 more
doaj +1 more source
Migration as a means of population control [PDF]
Population Studies, 1971 Abstract The more crowded West Indian islands lose citizens each year through emigration, and they are small enough for an appreciable relief of population pressure to be thereby afforded. Each year some of the inhabitants of Java move to Sumatra and elsewhere under official sponsorship, part of the rationale for the policy being the relief of ...
openaire +2 more sources
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Parametric and Semiparametric Model‐Based Estimates of the Finite Population Mean for Two‐Stage Cluster Samples with Item Nonresponse [PDF]
, 2007 Ying Yuan, Roderick J. A. Little
openalex +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Optimizing Finite Population Mean Estimation Using Simulation and Empirical Data
MathematicsTwo-phase sampling is an effective sampling approach that is useful in sample surveys when prior auxiliary information is not available. When two variables have an association, the ranks of the auxiliary variable are proportional to the study variable ...
Abdulaziz S. Alghamdi +1 more
doaj +1 more source