Population paths implied by the mean number of pairwise nucleotide differences among mitochondrial DNA sequences [PDF]
N. BONNEUIL
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Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Partial stratified ranked set sampling scheme for estimation of population mean and median. [PDF]
M M, Almanjahie IM, Ismail M, Cheema AN.
europepmc +1 more source
Improved ratio estimators of population mean using transformed variable in double sampling
Uraiwan Jaroengeratikun, Nuanpan Lawson
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We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Dual Use of Auxiliary Information for Estimating the Finite Population Mean under the Stratified Random Sampling Scheme [PDF]
Sohaib Ahmad +5 more
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Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Estimation of finite population mean using double sampling under probability proportional to size sampling in the presence of extreme values. [PDF]
Wang J +6 more
europepmc +1 more source
Modelled and observed mean and seasonal relationships between climate, population density and malaria indicators in Cameroon [PDF]
Amelie D. Mbouna +5 more
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Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source

