HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley +1 more source
eSRT Versus Population Mean: Setting Upper Stimulation Levels in Adult Cochlear Implant Users. [PDF]
Holder JT, MacDonald A, Gifford RH.
europepmc +1 more source
Generalized Neutrosophic Sampling Strategy for Elevated Estimation of Population Mean
Subhash Kumar Yadav +1 more
openalex +1 more source
Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi +7 more
wiley +1 more source
Does Femoral Rotation More Closely Mirror the Contralateral Side or a Population Mean of 15 Degrees of Anteversion? A Radiologic Study of 219 Healthy Patients. [PDF]
Anderson ML +6 more
europepmc +1 more source
Improving efficiency and robustness of the doubly robust estimator for a population mean with incomplete data [PDF]
Weihua Cao +2 more
openalex +1 more source
Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells
UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca +6 more
wiley +1 more source
Genetic divergence in population mean fitness is weakly associated with environmental and geographic distance in four prairie perennial forbs. [PDF]
Peschel AR, Flint SA, May G, Shaw RG.
europepmc +1 more source
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Evaluating ARG-estimation methods in the context of estimating population-mean polygenic score histories. [PDF]
Peng D, Mulder OJ, Edge MD.
europepmc +1 more source

