Results 261 to 270 of about 7,589,489 (318)

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky, Cara Joyce, H. Jeremy Bockholt, Paul A. Rudnick, William H. Adams, Fiona McAllister, Justin W. Smock, Michael A. Newton, Jane S. Paulsen   +8 more
wiley   +1 more source

Lessons Learned From a Delayed‐Start Trial of Modafinil for Freezing of Gait in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Freezing of gait (FOG) in people with Parkinson's disease (PwPD) is debilitating and has limited treatments. Modafinil modulates beta/gamma band activity in the pedunculopontine nucleus (PPN), like PPN deep brain stimulation. We therefore tested the hypothesis that Modafinil would improve FOG in PwPD.
Tuhin Virmani, Lakshmi Pillai, Reid D. Landes, Aliyah Glover, Shannon Doerhoff, Jennifer Kleiner, Mitesh Lotia, Rohit Dhall, Edgar Garcia‐Rill   +8 more
wiley   +1 more source

Predictors of carotenoid status in New Zealand children using carotenoid reflection score: a cross-sectional study. [PDF]

Asia Pac J Clin Nutr
Rapson J, Rush E, McLean R, Fuavao K, Wall C, Eyles H.   +5 more
europepmc   +1 more source

Sexual Selection Associated With an Aggressive Male Phenotype Reduces Population Size and Hinders Population Recovery After Heat Stress. [PDF]

Ecol Lett
Pandey N, Porwal N, Parrett JM, Radwan J, Knell RJ, Cameron TC.   +5 more
europepmc   +1 more source

Optimum recombination rates for genetic gains in simulated recurrent selection in empirical maize populations. [PDF]

Plant Genome
Anilkumar C, Bernardo R.
europepmc   +1 more source

Derivation of Expected Mean Squares in Variance Components Models Having Finite Populations

, 1969
S. R. Searle, Richard Fawcett
openalex   +1 more source

The correction of the urban-rural wealth Gini coefficient of China. [PDF]

PLoS One
Dai P, Jin Z.
europepmc   +1 more source

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The meaning of ‘populism’

Philosophy & Social Criticism, 2019
This essay presents a novel approach to specifying the meaning of the concept of populism, on the political position it occupies and on the nature of populism. Employing analytic techniques of concept clarification and recent analytic ideology critique, it develops populism as a political kind in three steps.
openaire   +1 more source

Comparing population mean curves

2001
Abstract One approach to the a posteriori classification of problem/algorithm combinations in the context of evolutionary algorithms (EAs), is to record and analyse a number of summary statistics of the evolution of the population. This paper discusses a necessary normalization of the population mean curve, i.e., the curve of the average fitness of ...
B. Naudts, I. Landrieu
openaire   +1 more source