Results 111 to 120 of about 876,447 (311)

From Natural Discovery to AI‐Guided Design: A Curated Collection of Compact Enhancers for Crop Engineering

open access: yesAdvanced Science, EarlyView.
ABSTRACT Precise transgene‐free gene upregulation remains a challenge in crop biotechnology, as conventional enhancers often exceed CRISPR‐mediated knock‐in size constraints and face regulatory hurdles. Here we establish a foundational cross‐species resource of compact transcriptional enhancers developed via STEM‐seq, a high‐throughput screening ...
Qi Yao   +14 more
wiley   +1 more source

Population oscillations in spatial stochastic Lotka-Volterra models: A field-theoretic perturbational analysis

open access: yes, 2012
Field theory tools are applied to analytically study fluctuation and correlation effects in spatially extended stochastic predator-prey systems. In the mean-field rate equation approximation, the classic Lotka-Volterra model is characterized by neutral ...
Tauber, Uwe C.
core   +1 more source

Multi‐Tissue Genetic Regulation of RNA Editing in Pigs

open access: yesAdvanced Science, EarlyView.
This study presents the first multi‐tissue map of RNA editing and its genetic regulation in pigs. By integrating RNA editing profiles, edQTL mapping, GWAS, and cross‐species comparisons, this work establishes RNA editing as a distinct regulatory layer linking genetic variation to complex traits, highlighting its functional and evolutionary significance.
Xiangchun Pan   +21 more
wiley   +1 more source

In-sample tests of predictive ability: a new approach [PDF]

open access: yes
This paper presents analytical, Monte Carlo, and empirical evidence linking in-sample tests of predictive content and out-of-sample forecast accuracy.
Michael W. McCracken, Todd E. Clark
core   +3 more sources

Critical Limitations in Cryogenic Laser Cooling of Solids: Symmetry‐Related Fluorescence Trapping and Condensation‐Induced Parasitic Heating

open access: yesAdvanced Science, EarlyView.
This study uncovers two overlooked bottlenecks in cryogenic laser cooling of solids: symmetry‐driven fluorescence trapping and water vapor condensation. We demonstrate that breaking sample symmetry enhances fluorescence escape, while condensation dominates parasitic heating below 135 K.
Biao Zhong   +5 more
wiley   +1 more source

Interacting multiple -- Try algorithms with different proposal distributions [PDF]

open access: yes
We propose a new class of interacting Markov chain Monte Carlo (MCMC) algorithms designed for increasing the efficiency of a modified multiple-try Metropolis (MTM) algorithm. The extension with respect to the existing MCMC literature is twofold.
Fabrizio Leisen   +2 more
core  

Nuclear Spin‐Free 70Ge/28Si70Ge Quantum Well Heterostructures Grown on Industrial SiGe‐Buffered Wafers

open access: yesAdvanced Science, EarlyView.
Hyperfine coupling to 29Si$^{29}{\rm Si}$ and 73Ge$^{73}{\rm Ge}$ nuclear spins limits hole spin‐qubit coherence in Ge heterostructures. We demonstrate device‐grade, nuclear‐spin‐free 70Ge$^{70}{\rm Ge}$/28Si70Ge$^{28}{\rm Si}^{70}{\rm Ge}$ quantum wells grown on industrial SiGe buffers with minimal use of enriched precursors.
Patrick Daoust   +11 more
wiley   +1 more source

Light‐Driven Competitive Selection in a Protein‐Catalyzed Dissipative Peptide Replication

open access: yesAngewandte Chemie, EarlyView.
A structurally flexible protein catalyzes replication within a dissipative reaction network driven by UVA‐induced disulfide rearrangements. The protein accelerates templated autocatalytic cycles with replication emerging as the dominant pathway.
Éva Bartus   +12 more
wiley   +2 more sources

Mechanistic Considerations for Battery Charging Protocol Design

open access: yesAdvanced Energy Materials, EarlyView.
This review bridges practical fast‐charging protocols with fundamental mechanisms of SOC‐dependent structural and compositional changes in electrode materials, kinetic limitations such as polarization and inhomogeneity, and heat generation characteristics shaped by protocol design.
Wenlong Li   +13 more
wiley   +1 more source

Computer simulations for biological aging and sexual reproduction

open access: yesAnais da Academia Brasileira de Ciências, 2001
The sexual version of the Penna model of biological aging, simulated since 1996, is compared here with alternative forms of reproduction as well as with models not involving aging.
DIETRICH STAUFFER   +4 more
doaj   +1 more source

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