Results 141 to 150 of about 876,447 (311)

Treatment of a large cohort of childhood chronic non‐infectious uveitis a multicentric large study: adalimumab versus methotrexate as first line therapy

Arthritis &Rheumatology, Accepted Article.
Background Treatment of childhood chronic idiopathic uveitis (cCIU) is predominantly based on studies in Juvenile Idiopathic Arthritis associated uveitis and expert opinion. Our aim was to report the treatment outcomes of our cohort of cCIU. Methods Retrospective multicenter study involving the rheuma/ophthalmology units at Florence and Bristol.
Ilaria Maccora, Catherine Guly, Cinzia de Libero, Giulia Carreras, Athimalaipet V. Ramanan, Gabriele Simonini   +5 more
wiley   +1 more source

Adeno‐associated virus serotype 2 capsid variants for improved liver‐directed gene therapy

Hepatology, EarlyView., 2022
Abstract Background and Aims Current liver‐directed gene therapies look for adeno‐associated virus (AAV) vectors with improved efficacy. With this background, capsid engineering is explored. Whereas shuffled capsid library screenings have resulted in potent liver targeting variants with one first vector in human clinical trials, modifying natural ...
Nadja Meumann, Marti Cabanes‐Creus, Moritz Ertelt, Renina Gale Navarro, Julie Lucifora, Qinggong Yuan, Karin Nien‐Huber, Ahmed Abdelrahman, Xuan‐Khang Vu, Liang Zhang, Ann‐Christin Franke, Christian Schmithals, Albrecht Piiper, Annabelle Vogt, Maria Gonzalez‐Carmona, Jochen T. Frueh, Evelyn Ullrich, Philip Meuleman, Steven R. Talbot, Margarete Odenthal, Michael Ott, Erhard Seifried, Clara T. Schoeder, Joachim Schwäble, Leszek Lisowski, Hildegard Büning   +25 more
wiley   +1 more source

Regional Shopping Objectives in British Grocery Retail Transactions Using Segmented Topic Models

Applied Stochastic Models in Business and Industry, EarlyView.
ABSTRACT Understanding the customer behaviours behind transactional data has high commercial value in the grocery retail industry. Customers generate millions of transactions every day, choosing and buying products to satisfy specific shopping needs.
Mariflor Vega Carrasco, Mirco Musolesi, Jason O'Sullivan, Rosie Prior, Ioanna Manolopoulou   +4 more
wiley   +1 more source

Optimized population Monte Carlo

Comment: 14 pages, 8 figures, submitted to the proceedings of ...
Ebert, P. L., Gessert, D., Janke, W., Weigel, M.   +3 more
openaire   +1 more source

Discovery and Initial Investigation of a New Low Surface Brightness Planetary Nebula Candidate at High Galactic Latitude

Astronomische Nachrichten, EarlyView.
ABSTRACT Planetary nebulae represent a late evolutionary phase of low‐ to intermediate‐mass stars. In this article, we present the serendipitous discovery of a previously unknown, faint potential Galactic planetary nebula (PN) in the constellation Camelopardalis, identified during a survey‐inspection, aiming at the detection of dwarf companions of the ...
W. E. Celnik, P. Köchling, S. Kotov, J. Kozok, Y. Galata, L. Magrini, A. Moiseev, M. Nischang, C. Reese, P. Remmel, P. Riepe, T. Zilch, K. Werner   +12 more
wiley   +1 more source

An Examination of Racial Bias in Scoring the Autism Diagnostic Observation Schedule (ADOS) Module 3: An Item Response Theory Analysis

Autism Research, EarlyView.
ABSTRACT Given the rising prevalence of autism among racial minority children in the United States, but persistent service use disparities, this study examines potential bias in specific items from the autism diagnostic observation schedule (ADOS), a highly regarded autism evaluation.
Yuen Yvonne Yu, Austin Wyman, Calliana J. Faulk, Lizzy J. Fulop, Rebecca L. Greenberg, Rachel M. Benecke, Lauren K. Steinbeck, Jessica Foy, Caitlyn Kim, George O. Emory, Eric A. Storch, Casey J. Zampella, Benjamin E. Yerys, Robert T. Schultz, Julia Parish‐Morris, John D. Herrington, Caitlin C. Clements   +16 more
wiley   +1 more source

Parental Stress and Caregiver Role Modulate Child–Caregiver Prosodic Synchrony in Autism: A Computational Analysis

Autism Research, EarlyView.
ABSTRACT Parental stress influences parent–child interactions in typical development and is a prognostic factor of autism outcome. However, we still do not know to what extent parental stress affects parent–child interactions and whether caregiver role matters.
Maria Grazia Logrieco, Giulio Bertamini, Laura Casula, Mohamed Chetouani, Silvia Guerrera, Mirco Fasolo, Paola Venuti, Maria Luisa Scattoni, Francesca Fulceri, Stefano Vicari, David Cohen, Giovanni Valeri   +11 more
wiley   +1 more source

A Hardware Generator of Multi-point Distributed Random Numbers for Monte Carlo Simulation [PDF]

Monte Carlo simulation of weak approximations of stochastic differential equations constitutes an intensive computational task. In applications such as finance, for instance, to achieve "real time" execution, as often required, one needs highly efficient
Eckhard Platen, Filippo Martini, Massimo Piccardi, Nicola Bruti-Liberati   +3 more
core  

Diffusion Coefficient and Viscosity of Methyl Viologen Electrolyte Estimation Based on a Kinetic Monte Carlo Computational Approach Coupled with the Mean Square Displacement Method

Batteries &Supercaps, Volume 8, Issue 3, March 2025.
A novel and comprehensive 3D‐resolved kinetic Monte Carlo model coupled with mean square displacement analysis is introduced. This computational approach allows to explore, for the first time, the concentration and the state of charge effects on ionic diffusion coefficient and viscosity in methyl viologen‐based electrolytes used in organic redox flow ...
Jia Yu, Emmanuel Baudrin, Alejandro A. Franco   +2 more
wiley   +1 more source

Cost‐utility analysis of nusinersen–risdiplam switch in patients with spinal muscular atrophy in Croatia: A discrete event simulation model

British Journal of Clinical Pharmacology, EarlyView.
Introduction In recent years, the treatment of spinal muscular atrophy (SMA), a rare disease, has significantly progressed, improving patients' survival and overall quality of life. However, current SMA treatments are expensive, and some (nusinersen) are very inconvenient for patients.
Andrej Belančić, Ivana Stević, Elvira Meni Maria Gkrinia, Dinko Vitezić, Slobodan Janković   +4 more
wiley   +1 more source