Results 171 to 180 of about 876,447 (311)

Early‐Life Clinical Factors Shape Cerebellar Structure in Preterm‐Born Children

Annals of the Child Neurology Society, EarlyView.
ABSTRACT Objective Preterm birth alters typical brain development due to complex exposures related to neonatal illness, pain management, and brain injury. Despite an increased understanding of neonatal brain injury on developmental outcomes, the association of cerebellar maturation with school‐age motor and cognitive function remains incompletely ...
Victoria Rapos, Steven Ufkes, Cecil Chau, Jessie van Dyk, Ting Guo, Ruth E. Grunau, Steven P. Miller   +6 more
wiley   +1 more source

Straight to Phase III: Model‐Informed Approach Speeds Depemokimab Clinical Development in Interleukin‐5‐Driven Diseases

Clinical Pharmacology &Therapeutics, EarlyView.
Straight to Phase III: Model‐informed approach speeds depemokimab clinical development in interleukin‐5‐driven diseases. IL‐5, a key mediator of type 2 inflammation, underlies various diseases, including severe asthma, CRSwNP, EGPA, and HES. Reduction in blood eosinophil count (BEC), a biomarker of IL‐5 activity, is commonly used to evaluate the ...
Chiara Zecchin, Stein Schalkwijk, Isabelle J. Pouliquen, Alienor Berges, Nicholas Bird, Richard Follows, Daren Austin   +6 more
wiley   +1 more source

Optimizing genomic sampling for demographic and epidemiological inference with Markov decision processes. [PDF]

Genetics
Rasmussen DA, Bursell MG, Burkhart F.
europepmc   +1 more source

Slip versus dilation tendency parameter space as a tool for prospecting structurally controlled geothermal systems in greenfield: insights from the greater Ruhr region

Deep Underground Science and Engineering, EarlyView.
This study highlights that with the static and time‐dependent evolution of slip versus dilation tendency parameter space, structurally controlled deep geothermal systems can be selected within areas of higher permeability and lower seismic hazard. Abstract Faults play a vital role in the Earth's hydraulic system by facilitating fluid flow when dilating
Michal Kruszewski, Alessandro Verdecchia, Oliver Heidbach, Rebecca M. Harrington, David Healy   +4 more
wiley   +1 more source

A Digital Twin Strategy Combined with a Monte Carlo Simulation Framework to Predict Outcomes in Patients with Unusual-Site Venous Thrombosis Treated with Direct Oral Anticoagulants Versus Vitamin K Antagonists Using Data from Real-World Populations. [PDF]

Clin Pract
Franco-Moreno A, Escobar-Curbelo L, Torres-Macho J, Muñoz-Rivas N, Ancos-Aracil CL, Martínez de la Casa-Muñoz A, Bustamante-Fermosel A, Arranz-García P, Casado-Suela MÁ.   +8 more
europepmc   +1 more source

The Prevention of Eating Disorders in Australian Adolescents: A Modeled Cost‐Effectiveness Study

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Prevention programs for eating disorders (EDs) have the potential to reduce the onset of these diseases and improve the mental health and well‐being of the general population. However, there is mixed evidence on whether routine implementation of such programs at the population level is cost‐effective.
Long Khanh‐Dao Le, Eng Joo Tan, Phillipa Hay, Jaithri Ananthapavan, Yong Yi Lee, Cathrine Mihalopoulos   +5 more
wiley   +1 more source

A Methodological Review of Simulation Studies Published in Pharmacoepidemiology and Drug Safety. [PDF]

Pharmacoepidemiol Drug Saf
Muddiman R, Battan FIA, Tazare J, Schultze A, Boland F, Perez T, Wei L, Walsh ME, Moriarty F.   +8 more
europepmc   +1 more source

Patterns of understorey bird diversity across Amazonian forests: survey effort and range maps predict local species richness

Ecography, EarlyView.
Species diversity typically increases from higher to lower latitudes, but the regional‐scale variation along this geographic gradient remains unclear. It has been suggested that species diversity throughout Amazonia generally increases westward toward the Andes, but this pattern and its environmental determinants require further investigation for most ...
Pilar L. Maia‐ Braga, Anderson S. Bueno, Marina F. A. Maximiano, Torbjørn Haugaasen, Marina Anciães, John G. Blake, Bette A. Loiselle, Sergio H. Borges, Juliana Menger, Sidnei Dantas, Ramiro D. Melinski, Affonso H. N. Souza, Fernando H. T. de Abreu, Roberta L. Boss, Carlos A. Peres   +14 more
wiley   +1 more source

From Agent-Based Markov Dynamics to Hierarchical Closures on Networks: Emergent Complexity and Epidemic Applications. [PDF]

Entropy (Basel)
Klimenko AY, Rozycki A, Lu Y.
europepmc   +1 more source

Precipitation and tree biomass correlate with the diversity and functional composition of tropical rainforest cricket assemblages across climate and disturbance gradients

Ecography, EarlyView.
Disturbance‐driven changes in rainforest structure and environmental conditions can alter ecosystem functioning, yet the consequences for invertebrate communities – key contributors to decomposition, herbivory, and trophic interactions – are not fully understood, particularly in relation to structural changes in vegetation.
Charlotte E. Raven, Andy G. Howe, David C. F. Rentz, Emma J. Mackintosh, Andrew R. Marshall, Helen F. Nahrung   +5 more
wiley   +1 more source