Results 71 to 80 of about 288,721 (267)

Population movements, borders, and Chagas disease. [PDF]

open access: yesMem Inst Oswaldo Cruz, 2022
Avaria A   +3 more
europepmc   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Mass movement study along BR-101 highway in Campos dos Goytacazes,RJ

open access: yesVértices, 2013
Mass movements are continuous natural phenomena and external dynamics, like weathering and erosion processes. The study presents an analysis of mass movements along the BR101 highway in Campos dos Goytacazes, Rio de Janeiro.
José Luiz Ernandes Dias Filho   +2 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

A new approach to historical migratory movements based on surnames: the case of Spain

open access: yesHumanities & Social Sciences Communications
A data mining technique called Self-Organized Maps (SOM) was used to select the surnames with populational information (monophyletic) to be used in the reconstruction of past demographic processes, in order to show the historical population migrations ...
Roberto Rodríguez-Díaz   +2 more
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Formation of kinetic organization of movements in ontogenesis in urban and rural children

open access: yesActa Biomedica Scientifica
Introduction. Movements influence child development throughout of life. Through movement, needs for play, communication, and learning are realized. Individual differences in movement formation are associated with many factors, including environmental ...
V. M. Polyakov   +4 more
doaj   +1 more source

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