Results 61 to 70 of about 1,056,579 (306)

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Under the Light of the Population Register Dated 1857 An Evaluation upon the Socio-Economic Lives of the Gypsy Living in İstanbul

Selçuk Üniversitesi Sosyal Bilimler Enstitüsü Dergisi, 2020
The Gypsy having abondoned India and scattered to different parts of the worls are known wiith different appelations such as“Gypsies”, “Zigeuner”, “Gitanos”, “Cigani”. The Gypsyies having become the focus of interest since the date the historical records
Ayşegül Kuş
doaj  

The burden of chickenpox disease in Sweden

BMC Infectious Diseases, 2016
Background Chickenpox vaccine is not included in the routine childhood vaccination programme in Sweden. The aim of this study was to estimate the baseline of national chickenpox disease burden, as comprehensive studies, required for an assessment ...
Katarina Widgren, Johan Giesecke, Lars Lindquist, Anders Tegnell   +3 more
doaj   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

A general temporal data model and the structured population event history register

Demographic Research, 2006
At this time there are 37 demographic surveillance system sites active in sub-Saharan Africa, Asia and Central America, and this number is growing continuously.
Samuel J. Clark
doaj  

Protective effects of statins on COVID-19 risk, severity and fatal outcome: a nationwide Swedish cohort study

Scientific Reports, 2022
The impact of statins on COVID-19 remains unclear. This study aims to investigate whether statin exposure assessed both in the population and in well-defined cohorts of COVID-19 patients may affect the risk and severity of COVID-19 using nationwide ...
Ailiana Santosa, Stefan Franzén, Jonatan Nåtman, Björn Wettermark, Ingela Parmryd, Fredrik Nyberg   +5 more
doaj   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Patient-reported outcome measures in arthroplasty registries: Report of the Patient-Reported Outcome Measures Working Group of the International Society of Arthroplasty RegistriesPart I. Overview and rationale for patient-reported outcome measures

Acta Orthopaedica, 2016
The International Society of Arthroplasty Registries (ISAR) Steering Committee established the Patient-Reported Outcome Measures (PROMs) Working Group to convene, evaluate, and advise on best practices in the selection, administration, and interpretation
Ola Rolfson, Kate Eresian Chenok, Eric Bohm, Anne Lübbeke, Geke Denissen, Jennifer Dunn, Stephen Lyman, Patricia Franklin, Michael Dunbar, Søren Overgaard, Göran Garellick, Jill Dawson, the Patient-Reported Outcome Measures Working Group of the International Society of Arthroplasty Registries   +12 more
doaj   +1 more source

Surveying immigrants in Southern Europe: Spanish and Italian strategies in comparative perspective

Comparative Migration Studies, 2017
Italy and Spain, as countries of recent immigration and high irregularity rates, have struggled to adapt their statistical system, especially their population registers, to adequately reflect the presence of an increasing number of immigrants in their ...
Inmaculada Serrano Sanguilinda, Elisa Barbiano di Belgiojoso, Amparo González Ferrer, Stefania Maria Lorenza Rimoldi, Gian Carlo Blangiardo   +4 more
doaj   +1 more source

Anvendelser av Norges historiske befolkningsregister

Heimen, 2020
Sammendrag Norge har et sentralt landsdekkende folkeregister som ble startet opp i 1964, og for mange personer inneholder data som går lenger tilbake. For tida bygger vi et Historisk befolkningsregister (HBR) tilbake til 1801.
Gunnar Thorvaldsen, Hilde L. Sommerseth, Lars Holden   +2 more
doaj   +1 more source