Results 151 to 160 of about 8,235,165 (300)
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
The Distribution of Order Statistics Under Sampling Without Replacement
Journal of Statistical Theory and Applications (JSTA)This paper examines the distribution of order statistics taken from simple-random-sampling without replacement (SRSWOR) from a finite population with values $$1,\dots ,N$$ 1 , ⋯ , N .
B. O’Neill
doaj +1 more source
Long-term population projections: Scenarios of low or rebounding fertility.
PLoS ONEThe size of the human population is projected to peak in the 21st century. But quantitative projections past 2100 are rare, and none quantify the possibility of a rebound from low fertility to replacement-level fertility.
Dean Spears +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Analysis of selection pressure exerted on Plasmopara viticola by organically based fungicides [PDF]
, 2006 Downy mildew is one of the most important grape diseases world-wide. The pathogen is a genetically highly diversified organism with a high capacity of adaptation. A monitoring of changes in population structure of P.
Gessler, C. +3 more
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Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Fractal and FractionalDengue fever, a mosquito-borne disease caused by the dengue virus, imposes a substantial disease burden on the world. Wolbachia not only manipulates the reproductive processes of mosquitoes through maternal inheritance and cytoplasmic incompatibility (CI)
Xianghong Zhang +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Collective and individual rationality: Robert Malthus’s heterodox theodicy [PDF]
, 2003 This paper forms part of a research project investigating conceptions of the relationship between micro-level self-seeking agent behaviour and the desirability or otherwise of the resulting macro-level social outcomes in the history of economics.
Denis, A.
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