Results 81 to 90 of about 8,235,165 (300)

Contribution of migration to replacement of population in Turkey [PDF]

Migration Letters, 2016
Relationship between migration and replacement of population has attracted a great deal of scholarly attention. Migration is considered to be a key factor in the growth and replacement of populations. Net migration sometimes exceeds natural change and drive population growth. Migration can compensate for missing births in low-fertility areas, provinces,
Ediev, D., Yüceşahin, M.M.
openaire   +2 more sources

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

The Main Cause of Death Following Primary Total Hip and Knee Replacement for Osteoarthritis:A Cohort Study of 26,766 Deaths Following 332,734 Hip Replacements and 29,802 Deaths Following 384,291 Knee Replacements [PDF]

, 2017
BACKGROUND: Patients undergoing primary total joint replacement are selected for surgery and thus (other than having a transiently increased mortality rate postoperatively) have a lower mortality rate than age and sex-matched individuals do ...
Ben-Shlomo, Yoav, Blom, Ashley, Hunt, Linda, Porter, Martyn, Whitehouse, Michael   +4 more
core   +2 more sources

Five-Year Outcomes of Transfemoral Transcatheter Aortic Valve Replacement or Surgical Aortic Valve Replacement in a Real World Population.

Circulation. Cardiovascular Interventions, 2019
BACKGROUND The OBSERVANT study (Observational Study of Effectiveness of SAVR-TAVI Procedures for Severe Aortic Stenosis Treatment) showed that mortality at 1 year is similar after transfemoral transcatheter aortic valve replacement (TAVR) or surgical ...
M. Barbanti, C. Tamburino, P. D'Errigo, F. Biancari, M. Ranucci, S. Rosato, G. Santoro, D. Fusco, F. Seccareccia   +8 more
semanticscholar   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Wolbachia infections that reduce immature insect survival: Predicted impacts on population replacement

BMC Evolutionary Biology, 2011
BackgroundThe evolutionary success of Wolbachia bacteria, infections of which are widespread in invertebrates, is largely attributed to an ability to manipulate host reproduction without imposing substantial fitness costs.
P. Crain, James W. Mains, Eunho Suh, Yunxin Huang, P. Crowley, S. Dobson   +5 more
semanticscholar   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Back to replacement migration: A new European perspective applying the prospective-age concept

Demographic Research, 2019
Background: The UN Replacement Migration report (2000) had a significant impact in academic and civil society. Its approach consisted of estimating the migration volumes required to mitigate the effects of population decline and ageing.
Daniela Craveiro, Isabel Tiago de Oliveira, Maria Cristina Sousa Gomes, Jorge Malheiros, Maria João Guardado Moreira, João Peixoto   +5 more
doaj   +1 more source

Adequacy of thyroid hormone replacement in a general population [PDF]

QJM, 2010
Suboptimal thyroid hormone replacement may carry harmful health consequences.Our objectives were to determine the prevalence and factors associated with inadequate replacement in patients receiving treatment with levothyroxine.Retrospective general practice audit.We identified levothyroxine users through electronic searches of primary care records in ...
O E, Okosieme, G, Belludi, K, Spittle, R, Kadiyala, J, Richards   +4 more
openaire   +2 more sources