Results 41 to 50 of about 477,954 (257)

Adapting non-invasive human recordings along multiple task-axes shows unfolding of spontaneous and over-trained choice

open access: yeseLife, 2021
Choices rely on a transformation of sensory inputs into motor responses. Using invasive single neuron recordings, the evolution of a choice process has been tracked by projecting population neural responses into state spaces. Here, we develop an approach
Yu Takagi   +4 more
doaj   +1 more source

Genetic drift suppresses bacterial conjugation in spatially structured populations [PDF]

open access: yesBiophysical Journal, 2014
ABSTRACT Conjugation is the primary mechanism of horizontal gene transfer that spreads antibiotic resistance among bacteria. Although conjugation normally occurs in surface-associated growth (e.g., biofilms), it has been traditionally studied in well-mixed liquid cultures lacking spatial structure, which is known to ...
Freese, PD   +3 more
openaire   +6 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Environmental Brownian noise suppresses explosions in population dynamics

open access: yesStochastic Processes and their Applications, 2002
It is well known that by adding a noise term to the right hand side of an ordinary differential equation it is often possible to change completely stability properties of solutions. In particular, solutions to a stochastic differential equation may exist globally while solutions to the corresponding deterministic problem blow up in finite time.
Mao, Xuerong   +2 more
openaire   +4 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Modelling the suppression of a malaria vector using a CRISPR-Cas9 gene drive to reduce female fertility

open access: yesBMC Biology, 2020
Background Gene drives based on CRISPR-Cas9 technology are increasingly being considered as tools for reducing the capacity of mosquito populations to transmit malaria, and one of the most promising options is driving endonuclease genes that reduce the ...
Ace R. North   +2 more
doaj   +1 more source

Lab-scale characterization and semi-field trials of Wolbachia Strain wAlbB in a Taiwan Wolbachia introgressed Ae. aegypti strain.

open access: yesPLoS Neglected Tropical Diseases, 2022
Dengue fever is one of the most severe viral diseases transmitted by Aedes mosquitoes, with traditional approaches of disease control proving insufficient to prevent significant disease burden.
Wei-Liang Liu   +12 more
doaj   +1 more source

An investigation of weight suppression in a population‐based sample of female twins [PDF]

open access: yesInternational Journal of Eating Disorders, 2010
AbstractObjective:Weight suppression (WS), maintaining a body weight below one's maximum adult weight, is associated with bingeing, purging, and weight gain in clinical samples.Method:We investigated associations between eating disorder‐related variables and WS and additive genetic (A), common (C), and unique (E) environmental contributions to WS in a ...
Karen S, Mitchell   +6 more
openaire   +2 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Pengendalian Aphis craccivora Koch. dengan kitosan dan pengaruhnya terhadap penularan Bean common mosaic virus strain Black eye cowpea (BCMV-BlC) pada kacang panjang

open access: yesJurnal Entomologi Indonesia, 2015
Aphis craccivora is one of the important pests on yard long bean. It causes direct damage and also has an indirect effect as insect vector of the Bean common mosaic virus (BCMV).
Dita Megasari   +2 more
doaj   +1 more source

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