Results 171 to 180 of about 536,545 (247)
OPTRACE: Optical Imaging–Guided Transplantation and Tracking of Cells in the Mouse Brain
OPTRACE establishes an optical, two‐step platform for intracerebral cell therapy. Transparent glass pipettes enable real‐time, image‐guided delivery, while multiplex genetic labeling with two‐photon and bioluminescence readouts supports longitudinal single‐cell tracking and host–graft dynamics.
Jinghui Wang +10 more
wiley +1 more source
Molecular Characterization of Plasmodium Species to Strengthen Malaria Surveillance in Migrant Populations in Honduras [PDF]
Alcides Godoy +6 more
openalex +1 more source
Single‐cell profiling across bone marrow, spleen, mesenteric lymph, and blood in rhesus monkeys reveals organ Immunosenescence. GZMB rises with age, particularly in cytotoxic and terminally exhausted CD8+ T cells, and BHLHE40 emerges as a key transcription factor enriched across multiple CD8+ subsets, regulating pro‐inflammatory and exhaustion‐related ...
Shengnan Wang +10 more
wiley +1 more source
A CD169+ macrophage‐targeted immunomodulator (G‐LNP@S‐D) is developed to co‐deliver a SHP2 inhibitor and STING agonist, thereby restoring phagocytic function, enhancing antigen presentation by CD169+ macrophages, and promoting T cell priming to eradicate lymphatic metastasis.
Xiayun Chen +9 more
wiley +1 more source
Current understanding of gastric cancer immunity remains inadequate, leading to suboptimal immunotherapy outcomes. This study introduces a novel tumor immune microenvironment classification system (Inflamed, Desert, and Excluded), advancing traditional histopathological or molecular subtyping toward a functional immunological framework.
Jianchao Wang +14 more
wiley +1 more source
KNOWLEDGE OF THE POPULATION RECIFE ABOUT HEALTH SURVEILLANCE
Fábia Alexandra Pottes Alves +3 more
openalex +2 more sources
GlycoChat Uncovers Glycan–Lectin Circuits in the Tumor Microenvironment of Pancreatic Cancer
Aberrant glycosylation drives cancer progression, yet its role in the tumor microenvironment remains unclear. We developed GlycoChat to map glycan–lectin circuits at single‐cell resolution. We discovered that cancer cells induce immunosuppressive macrophage differentiation and impair phagocytosis through interactions with CLEC10A and SIGLEC3 ...
Dinh Xuan Tuan Anh +8 more
wiley +1 more source

