Results 231 to 240 of about 536,545 (247)

Trojan Horse Strategy: How Biomimetic Nanomedicine Remodels the Tumor Microenvironment

Advanced Science, EarlyView.
This review focuses on biomimetic nanomedicines for tumor microenvironment (TME) remodeling, covering their diverse biomimetic types, design principles, and mechanisms of immune cell reprogramming and reversal of immunosuppressive microenvironments, with particular emphasis on their application in synergistic immunotherapy.
Wanrong Wang, Siqi Mu, Juan Zhang, Guisong Shan, Xueqian Li, Ran Wang, Tao Guo, Xiaoyan He   +7 more
wiley   +1 more source

Heterointerface‐Functionalized Photoelectric Response of Metal‐Oxide Schottky Photodiode for Intelligent Fire Detection

Advanced Science, EarlyView.
A heterointerface‐functionalized Schottky photodiode (HF‐SPD) is developed to explore the photoelectric capabilities of low‐temperature oxide semiconductors. Besides the remarkable UV detection capability, the bias‐tunable photo response endows HF‐SPD with the unique wavelength selectivity.
Yuyang Cai, Zhiwei Zheng, Zhiwu Zhong, Yuhan Zhang, Tengyan Huang, Yucheng Cao, Dawei Zheng, Yen Hung Lin, Fion Sze Yan Yeung, Kuan‐Chang Chang, Jie Chen, Hoi Sing Kwok, Lei LU, Yufeng Jin   +13 more
wiley   +1 more source

Trends in mortality rates of female breast cancer in China, 2004 to 2021. [PDF]

Medicine (Baltimore)
Xiong H, Ma F.
europepmc   +1 more source

Resilient Calvarial Bone Marrow Supports Retinal Repair in Type 2 Diabetes

Advanced Science, EarlyView.
Skull bone (calvarium) marrow in diabetic mice stay structurally intact and keeps making blood cells, unlike the bone marrow of the leg bones. The skull marrow is exposed to cerebrospinal fluid (CSF), which contains protective molecules called oxysterols.
Bright Asare‐Bediako, Sergio Li Calzi, Julia G. Behnsen, Ram Prasad, Magdalena Blaszkiewicz, Yvonne Adu‐Rutledge, Robert F. Rosencrans, Jason L. Floyd, Ashley Rennhack, Denise Stanford, Anna Lin, Todd A. Lydic, Carl M. Sheridan, Michael E. Boulton, Kristy L. Townsend, Julia V. Busik, Maria B. Grant   +16 more
wiley   +1 more source

Cell‐Free DNA‐Based Theranostics for Inflammatory Disorders

Advanced Science, EarlyView.
Summary on the dual potential of cfDNA as biomarkers and therapeutic targets for inflammatory disorders. Figure was created with BioRender.com. ABSTRACT Inflammatory disorders are characterized by immune‐mediated inflammatory cascades that can affect multiple organs.
Jiatong Li, Yumei Wang, Xiaoxi Fan, Miao Xu, Jiawen Li, Wenfei Tan, Jianxiang Zhang, Heran Li   +7 more
wiley   +1 more source

COVID-19 testing and reporting behaviours in England across different sociodemographic groups: a population-based study using testing data and data from community prevalence surveillance surveys

Sumali Bajaj, Siyu Chen, Richard Creswell, Reshania Naidoo, Joseph L.-H. Tsui, Olumide Kolade, George Nicholson, Brieuc Lehmann, James A. Hay, Moritz U. G. Kraemer, Ricardo Aguás, Christl A. Donnelly, Tom Fowler, Susan Hopkins, Liberty Cantrell, Prabin Dahal, Lisa J. White, Kasia Stepniewska, Merryn Voysey, Ben Lambert, Ricardo Aguas, Ma'ayan Amswych, Billie Andersen-Waine, Sumali Bajaj, Kweku Bimpong, Adam Bodley, Liberty Cantrell, Siyu Chen, Richard Creswell, Prabin Dahal, Sophie Dickinson, Sabine Dittrich, Tracy Evans, Angus Ferguson-Lewis, Caroline Franco, Bo Gao, Rachel Hounsell, Muhammad Kasim, Claire Keene, Ben Lambert, Umar Mahmood, Melinda Mills, Ainura Moldokmatova, Sassy Molyneux, Reshania Naidoo, Randolph Ngwafor Anye, Jared Norman, Wirichada Pan-Ngum, Sunil Pokharel, Anastasiia Polner, Emily Rowe, Sompob Saralamba, Rima Shretta, Sheetal Silal, Kasia Stepniewska, Joseph L-H Tsui, Merryn Voysey, Marta Wanat, Lisa J White   +58 more
openalex   +1 more source

T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities

Advanced Science, EarlyView.
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu, Xiaoyu Yao, Qingyang Wang, Mengrui Yang, Runze Li, Jiangjiang Qin, Jing Zhuang, Changgang Sun   +7 more
wiley   +1 more source

Integrated Ultrasound Device for Precision Bladder Volume Monitoring via Acoustic Focusing and Machine Learning

Advanced Science, EarlyView.
We present a conformable wearable ultrasound patch for noninvasive bladder volume monitoring. A flexible PZT array combined with a concave acoustic lens concentrates acoustic energy and improves depth selectivity through the anterior pelvic wall.
Long Long Cao, Feng Wen Wang, Jingwei Xue, Fulei Liu, Ming Liang Jin   +4 more
wiley   +1 more source

Leptospirosis in the Caribbean Region between 2000 and 2022: A scoping review of morbidity and mortality. [PDF]

PLoS Negl Trop Dis
Martin BM, Zhang Z, Vernal S, Jian H, Nilles EJ, Furuya-Kanamori L, Sartorius B, Lau CL.   +7 more
europepmc   +1 more source

Model-guided geospatial surveillance system for antimalarial drug resistance. [PDF]

PLOS Glob Public Health
Gupta A, Harrison LE, Nain M, Phulgenda SS, Chhajed R, Kumar RS, Das A, Rahi M, Guerin PJ, Anvikar AR, Dhorda M, Flegg JA, Bharti PK.   +12 more
europepmc   +1 more source