Results 51 to 60 of about 5,987,732 (303)

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Comparative analysis of COVID-19 and influenza prevalence among Egyptian pilgrims returning from Hajj and Umrah in 2022: epidemiology, clinical characteristics, and genomic sequencing

Archives of Public Health
Purpose To describe the changes that occurred in the SARS-CoV-2 and influenza Prevalence, epidemiology, clinical picture, and prevalent genotypes among the Egyptian pilgrims returning from Hajj and Umrah 2022 seasons.
Amr Kandeel, Manal Fahim, Ola Deghedy, Hala BahaaEldin, Wael H. Roshdy, Mohamed Kamal Khalifa, Ahmed Kandeil, Rabeh El Shesheny, Amel Naguib, Mohamad AbdelFatah, Salma Afifi, Khaled Abdel Ghaffar   +11 more
doaj   +1 more source

Filing for Workers’ Compensation among Ontario Cases of Mesothelioma

Canadian Respiratory Journal, 2009
BACKGROUND/OBJECTIVE: For many types of cancer, disease attribution to occupational exposures is difficult. Mesothelioma, however, is a ‘sentinel’ occupational cancer associated with asbestos exposure.
Jennifer Isabelle Payne, Erin Pichora
doaj   +1 more source

Global emergence and evolutionary dynamics of bluetongue virus

Scientific Reports, 2020
Bluetongue virus (BTV) epidemics are responsible for worldwide economic losses of up to US$ 3 billion. Understanding the global evolutionary epidemiology of BTV is critical in designing intervention programs.
Moh A. Alkhamis, Cecilia Aguilar-Vega, Nicholas M. Fountain-Jones, Kai Lin, Andres M. Perez, José M. Sánchez-Vizcaíno   +5 more
doaj   +1 more source

High Prevalence of Asymptomatic Intracranial Atherosclerosis in Elder Women With Tubal Ligation: Result From a Community-Based Study in Shandong, China

Frontiers in Cardiovascular Medicine, 2022
BackgroundIn addition to traditional cardiovascular risk factors, gender-specific factors may also contribute to intracranial atherosclerosis.
Xiaotong Ma, Shaowei Sang, Yuanyuan Zhao, Xiang Wang, Xiaokang Ji, Sai Shao, Guangbin Wang, Fuzhong Xue, Yifeng Du, Ming Lv, Qinjian Sun   +10 more
doaj   +1 more source

Surveillance for Hepatocellular Carcinoma in a Medicaid Cirrhotic Population

Journal of Clinical Gastroenterology, 2013
To estimate hepatocellular carcinoma surveillance in the Medicaid cirrhotic population.
Lena B, Palmer, Michael D, Kappelman, Robert S, Sandler, Paul H, Hayashi   +3 more
openaire   +3 more sources

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Age of smoking initiation and risk of breast cancer in a sample of Ontario women

Tobacco Induced Diseases, 2010
Objectives To examine the association between time of smoking initiation and both the independent and joint effects of active and passive tobacco smoke exposure and the risk of breast cancer in a sample of Ontario women.
Erin Young, Scott T. Leatherdale, Margaret Sloan, Nancy Kreiger, Andriana Barisic   +4 more
doaj   +1 more source

A Preliminary Study on the Ability of the Trypsin-Like Peptidase Activity Assay Kit to Detect Periodontitis

Dentistry Journal, 2020
This study aimed to explore whether the Trypsin-Like Peptidase Activity Assay Kit (TLP-AA-Kit), which measures the activity of N-benzoyl-dl-arginine peptidase (trypsin-like peptidase), can be used as a reliable tool for periodontitis detection in ...
Masanori Iwasaki, Michihiko Usui, Wataru Ariyoshi, Keisuke Nakashima, Yoshie Nagai-Yoshioka, Maki Inoue, Tatsuji Nishihara   +6 more
doaj   +1 more source