Results 131 to 140 of about 4,869,573 (245)

A Computational Framework for Myelin as a Regulator of Temporal Integration, Neuronal Excitability, and Synaptic Plasticity. [PDF]

Glia
O'Sullivan D, Pariz A, Trotter D, Al Dahhan NZ, Knowles JK, Frankland PW, Mabbott D, Lefebvre J.   +7 more
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Variation among populations of Quercus macrocarpa in a reciprocal transplant experiment across a latitudinal gradient. [PDF]

Ecology
Rea LMS, Ostrowsky L, Mohn R, Garner M, Worcester L, Lapadat C, McCarthy HR, Hipp AL, Cavender-Bares J.   +8 more
europepmc   +1 more source

Annual Report 2023-2024: Library Services to Multicultural Populations Section

Annual Report 2023-2024 of the IFLA Library Services to Multicultural Populations ...
Library Services to Multicultural Populations Section
core  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Mental health disparities in LGBTQIA+ populations: an umbrella review of systematic reviews and meta-analyses. [PDF]

World Psychiatry
Oliva V, Radua J, De Prisco M, Cerioli M, Bort M, Possidente C, Bracco L, Anmella G, Salazar de Pablo G, Fico G, Vieta E.   +10 more
europepmc   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Multiplayer social dilemmas in completely mixed populations and networks of mixing communities. [PDF]

J Math Biol
Pires DL, Broom M.
europepmc   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Whole-Genome Resequencing Reveals the Genetic Diversity and Adaptive Evolution of <i>Rhabdophis nuchalis</i>. [PDF]

Ecol Evol
Wu F, Jiang JY, Liang PW, Chen J, Fan LP, Zhou X, Wang J, Duan MW, Cheng YQ, Zhu GX.   +9 more
europepmc   +1 more source