Results 201 to 210 of about 3,957,884 (246)

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Evaluation of Field Variation in Flower Thrips, <i>Frankliniella intonsa</i> Trybom to Spinosoid Insecticide in Inner Mongolia, China. [PDF]

Insects
Bao W, Wu N, Angeer, Hubhachen Z, Gao Y.
europepmc   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Rapid evolution in necromass use under resource limitation reduces persistence in producer-decomposer microbial biospheres. [PDF]

Commun Biol
Jiang S, Halbleib A, Antonovics J, Remus-Emsermann M, Rillig MC, Mansour I.   +5 more
europepmc   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Reduced Genetic Load and Inbreeding in Reintroduced African Wild Dogs Reflect the Benefits of Admixture. [PDF]

Mol Ecol
Tensen L, Wang X, Watermeyer J, du Plessis C.   +3 more
europepmc   +1 more source

Investigation of Pharmacogenomic Variants in the CYP (P450) Family in Native American Populations of the Brazilian Amazon. [PDF]

Int J Genomics
de Freitas LM, Marcellino JCR, de Moraes FCA, Monte N, da Costa ACA, de Cássia Calderaro Coelho R, Aguiar KEC, Dos Santos AMR, Guerreiro JF, Dos Santos ÂR, Dos Santos SEB, Fernandes MR, Dos Santos NPC.   +12 more
europepmc   +1 more source

Genetic diversity, population structure, and combined detection of selection signatures in Iranian versus Afghan Baluchi sheep. [PDF]

PLoS One
Taheri S, Karimi MO, Saedi N, Zerehdaran S, Shariati MM, Gholizadeh M, Javadmanesh A.   +6 more
europepmc   +1 more source