Results 201 to 210 of about 205,786 (267)

Recent advances in the construction of humanized animal models and applications in translational medicine

Animal Models and Experimental Medicine, EarlyView.
Substantial advances have been achieved in the development of humanized mouse models, which have proven highly valuable in evaluating cancer immunotherapies and elucidating the mechanisms of infectious diseases. There is now a growing shift in research toward larger animal models—such as pigs—that offer greater physiological similarity to humans ...
Yanan Lyu, Yong‐Guang Yang, Zheng Hu
wiley   +1 more source

Toxicological effects of acrylamide on oocyte maturation and subsequent embryonic development in a porcine model. [PDF]

Biol Direct
Oh NG, Jeong PS, Kang HG, Jeon SB, Yun JH, Eom SY, Kim SU, Cho SK, Sim BW.   +8 more
europepmc   +1 more source

Tensile Stimulation in Biorelevant Culture Conditions Enhances MSC and TPSC Tenogenesis on Aligned Electrospun Scaffolds

Advanced NanoBiomed Research, EarlyView.
Biomimetic electrospun scaffold incorporating GDF‐7‐loaded mesoporous silica nanoparticles, combined with mechanical stimulation and physiological oxygen tension, guides tenogenic differentiation of mesenchymal stromal cell and tendon progenitor stem cell. This integrated approach enhances cell proliferation, matrix deposition, and tendon‐specific gene
Vera Citro, Aldo R. Boccaccini, Nicholas R. Forsyth, Tina P. Dale   +3 more
wiley   +1 more source

Concomitant Infection With Porcine circovirus 2 and Porcine Epidemic Diarrhea Virus Does Not Increase Enteritis Severity in Experimentally Infected Weaned Piglets. [PDF]

Transbound Emerg Dis
Gerber PF, Zhang J, Noel A, Wang B, Huang Y, Halbur PG, Opriessnig T.   +6 more
europepmc   +1 more source

Protocol for the isolation, culturing, and evaluation of primary Müller glial cells from pig retina as cellular models in health and disease. [PDF]

STAR Protoc
Tütüncü Y, Motlik J, Klymiuk N, Wolfrum U.   +3 more
europepmc   +1 more source

Landscape of N⁶-methyladenosine (m⁶A) methylation in porcine cells identifies candidate genes associated with porcine epidemic diarrhea virus infection. [PDF]

Front Microbiol
Dong X, Zhang Y, Wang Y, Wang C, Zhou A.
europepmc   +1 more source

Single-cell transcriptomic and chromatin accessibility atlas of peripheral blood mononuclear cells reveals immune cell heterogeneity and breed-specific characteristics in Duroc and Meishan pigs. [PDF]

BMC Genomics
Fan H, Du C, Xu C, Wang H, Wang Y, Wu Z, Zhao B, Chen C, Shang S, Sun MA, Bao W.   +10 more
europepmc   +1 more source

What's Hot and What's New in Xenotransplantation From the Young Investigator Committee of the IXA-Basic and Translational Science. [PDF]

Xenotransplantation
Goerlich CE, Salvaris EJ, Fischer K, Citro A, Giarraputo A, Ladowski J, Mazancourt ES, Wang L, Eisenson D, Connolly MR, Stern J, Longchamp A, Meier RPH.   +12 more
europepmc   +1 more source