Results 31 to 40 of about 205,786 (267)

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

Unraveling the impact of hyperleptinemia on female reproduction: insights from transgenic pig model

Biological Research
Background Infertility is a growing global health concern affecting millions of couples worldwide. Among several factors, an extreme body weight adversely affects reproductive functions. Leptin is a well-known adipokine that serves as an endocrine signal
Muhammad Ameen Jamal, Yixiao Cheng, Deling Jiao, Wen Cheng, Di Zou, Xia Wang, Taiyun Wei, Jianxiong Guo, Kaixiang Xu, Heng Zhao, Shaoxia Pu, Chang Yang, Yubo Qing, Baoyu Jia, Honghui Li, Rusong Zhao, Hong-Ye Zhao, Hong-Jiang Wei   +17 more
doaj   +1 more source

A Quadruplex RT-qPCR for the Detection of Porcine Sapelovirus, Porcine Kobuvirus, Porcine Teschovirus, and Porcine Enterovirus G

Animals
Porcine sapelovirus (PSV), porcine kobuvirus (PKV), porcine teschovirus (PTV), and porcine enterovirus G (EV-G) are all important viruses in the swine industry. These viruses play important roles in the establishment of similar clinical signs of diseases in pigs, including diarrhea, encephalitis, and reproductive and respiratory disorders.
Biao Li, Kaichuang Shi, Yuwen Shi, Shuping Feng, Yanwen Yin, Wenjun Lu, Feng Long, Zuzhang Wei, Yingyi Wei   +8 more
openaire   +3 more sources

A porcine model of osteosarcoma [PDF]

Oncogenesis, 2016
AbstractWe previously produced pigs with a latent oncogenic TP53 mutation. Humans with TP53 germline mutations are predisposed to a wide spectrum of early-onset cancers, predominantly breast, brain, adrenal gland cancer, soft tissue sarcomas and osteosarcomas. Loss of p53 function has been observed in >50% of human cancers.
Saalfrank, A, Janssen, K-P, Ravon, M, Flisikowski, K, Eser, S, Steiger, K, Flisikowska, T, Müller-Fliedner, P, Schulze, É, Brönner, C, Gnann, A, Kappe, E, Böhm, B, Schade, B, Certa, U, Saur, D, Esposito, I, Kind, A, Schnieke, A   +18 more
openaire   +2 more sources

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Effect of Extended Photoperiod on Performance, Health, and Behavioural Parameters in Nursery Pigs

Veterinary Sciences, 2023
Lighting influences the circadian rhythm and physiology of animals. Yet, the influence of light on nursery pigs is not fully understood and results remain controversial.
Friso Griffioen, Marijke Aluwé, Dominiek Maes   +2 more
doaj   +1 more source

Development of a Quadruplex RT-qPCR for the Detection of Porcine Astrovirus, Porcine Sapovirus, Porcine Norovirus, and Porcine Rotavirus A

Pathogens
Porcine astrovirus (PoAstV), porcine sapovirus (PoSaV), porcine norovirus (PoNoV), and porcine rotavirus A (PoRVA) are newly discovered important porcine diarrhea viruses with a wide range of hosts and zoonotic potential, and their co-infections are often found in pig herds.
Junxian He, Kaichuang Shi, Yuwen Shi, Yanwen Yin, Shuping Feng, Feng Long, Sujie Qu, Xingju Song   +7 more
openaire   +3 more sources

Natural Bone‐Derived Ceramic Scaffolds Functionalized with Chitosan‐Gold, Chitosan‐Magnesium, and Chitosan‐Zinc for Enhanced Antibacterial Activity

Advanced Engineering Materials, EarlyView.
This study reports the development of antibacterial ceramic scaffolds derived from natural bovine bone. The bones were processed through sequential boiling and hydrogen peroxide treatment to remove organic matter, producing porous, mineral‐rich scaffolds.
Mohamad Hassan Taherian, Anh Thi Le, Anh Thi Van Le, Dung My Thi Dang, Tin Chanh Duc Doan, Chien Mau Dang, Martin Bolduc   +6 more
wiley   +1 more source

Construction of TERT Monoallelic Knockout and TERT Overexpression of Porcine Cell Lines and Study of the Cellular Biological Characteristics

Animals
Telomerase reverse transcriptase subunit (TERT) is a key factor involved in telomere maintenance and genome stability, and the decline in its expression is closely related to cellular senescence.
Yanhong Yang, Xiaojing Chen, Jing Wang, Jingjing Xiong, Xiaoyin Zhang, Jiaoxiang Wang, Weiwei Xu, Yubo Qing, Honghui Li, Hong-Ye Zhao   +9 more
doaj   +1 more source

Short Communication: effect of positive handling of sows on litter performance and pre-weaning piglet mortality

Animal, 2020
Fear and environmental stressors may negatively affect the welfare of farm animals such as pigs. The present study investigated the effects of music and positive handling on reproductive performance of sows (n = 1014; parity 1 to 8) from a commercial pig
D. De Meyer, A. Amalraj, T. Van Limbergen, M. Fockedey, S. Edwards, V.A. Moustsen, I. Chantziaras, D. Maes   +7 more
doaj   +1 more source