Examining the potential for porcine-derived islet cells to harbour viral pathogens [PDF]
With an onus on safety in the potential use of porcine islet cells as a treatment for diabetes, the use of animals lacking exogenous pathogens is clearly important and multilevel screening strategies have been presented on testing animals and the product.
Crossan, Claire +4 more
core +2 more sources
Complete Genome Sequence of the Rearranged Porcine Circovirus Type 2 [PDF]
ABSTRACT We first report here the genome sequences of 4 rearranged porcine circovirus type 2 strains, JSTZ, ZJQDH1, ZJQDH2, and JSHM, isolated from porcine sera in China. The complete circular genomes of these isolates are 578, 483, 574, and 772 nucleotides in length, respectively.
Libin, Wen +11 more
openaire +2 more sources
ORAL IMMUNOGENICITY OF A PLANT VIRUS VECTOR BASED PORCINE CIRCOVIRUS ANTIGEN [PDF]
A recombinant cucumber mosaic virus based expression system has been developed for the production of an immunogenic porcine circovirus epitope. The resulting nanoparticle was shown to elicit specific immune response in mice and pigs, when administered
Balázs, Ervin +4 more
core +1 more source
In Vitro Intragenomic Rearrangement of Porcine Circovirus Type 2 [PDF]
ABSTRACT We report here for the first time the genome sequence of a rearranged porcine circovirus type 2 (PCV2) strain, CH-IVT1, isolated from PCV2-infected PK-15 cells. The complete circular genome of the CH-IVT1 is 605 nucleotides (nt) in length.
Libin, Wen +11 more
openaire +2 more sources
Protein Interactions Network of Porcine Circovirus Type 2 Capsid With Host Proteins
Virus-host interaction is a tug of war between pathogenesis and immunity, followed by either activating the host immune defense system to eliminate virus or manipulating host immune control mechanisms to survive and facilitate virus propagation ...
Jianwei Zhou +8 more
semanticscholar +1 more source
Genetic analysis of porcine circovirus type 2 from dead minks
Circovirus infection is a growing problem in the field of veterinary and public health. It is associated with enteric diseases in both mammalian and avian hosts. In this study, we detected and isolated porcine circovirus strains in the tissue samples of minks that died from diarrhoea in Shandong Province, China.
Gui-Sheng, Wang +7 more
openaire +2 more sources
Background In this study we utilized padlock probes and rolling circle amplification as a mean to detect and study the replication of porcine circovirus type 2 (PCV2) in cultured cells and in infected tissue.
Berg Mikael +5 more
doaj +1 more source
Hsp70 positively regulates porcine circovirus type 2 replication in vitro
The Hsp70 chaperone plays a central role in multiple processes within cells. Porcine circovirus type 2 (PCV2) is the essential causal agent of post-weaning multisystemic wasting syndrome (PMWS), which has spread worldwide. But the mechanism of PCV2 replication remains poorly understood. In this study, we firstly found the positive effect of heat stress
Liu, Jie +6 more
openaire +3 more sources
Co-expression of Ubiquitin gene and capsid protein gene enhances the potency of DNA immunization of PCV2 in mice [PDF]
A recombinant plasmid that co-expressed ubiquitin and porcine circovirus type 2 (PCV2) virus capsid protein (Cap), denoted as pc-Ub-Cap, and a plasmid encoding PCV2 virus Cap alone, denoted as pc-Cap, were transfected into 293T cells.
Fang Fu +7 more
core +2 more sources
Retrospective study of porcine circovirus type 2 infection reveals a novel genotype PCV2f.
Porcine postweaning multisystemic wasting syndrome (PMWS) caused by porcine circovirus type 2 (PCV2) is a disease causing severe economic losses annually worldwide to the pig industry. PCV2 infection was first reported in China in 2000, and currently has
F. Bao +7 more
semanticscholar +1 more source

