Type IV fimbrial subunit protein ApfA contributes to protection against porcine pleuropneumonia [PDF]
Veterinary Research, 2012 Porcine pleuropneumonia caused by Actinobacillus pleuropneumoniae accounts for serious economic losses in the pig farming industry worldwide. We examined here the immunogenicity and protective efficacy of the recombinant type IV fimbrial subunit protein ...
Sadilkova Lenka +4 more
doaj +5 more sources
The RNA chaperone Hfq promotes fitness of Actinobacillus pleuropneumoniae during porcine pleuropneumonia. [PDF]
Infect Immun, 2013 ABSTRACT Actinobacillus pleuropneumoniae is the etiological agent of porcine pleuropneumonia, an economically important disease of pigs. The hfq gene in A. pleuropneumoniae , encoding the RNA chaperone and posttranscriptional regulator Hfq, is upregulated during ...
Subashchandrabose S +4 more
europepmc +5 more sources
Candidate genes and gene markers for the resistance to porcine pleuropneumonia. [PDF]
Mamm Genome, 2020 AbstractActinobacillus(A.)pleuropneumoniaeis one of the most important respiratory pathogens in global pig production. Antimicrobial treatment and vaccination provide only limited protection, but genetic disease resistance is a very promising alternative for sustainable prophylaxis.
Nietfeld F +7 more
europepmc +6 more sources
Genome analysis of Actinobacillus pleuropneumoniae strain APPFJLYC01 reveals multidrug resistance and high virulence potential. [PDF]
PLoS ONEActinobacillus pleuropneumoniae is the primary etiological agent of porcine contagious pleuropneumonia, a devastating respiratory disease that causes substantial economic losses to the global swine industry.
Zhihong Fang +7 more
doaj +2 more sources
Field Evaluation of a Ready-to-Use Porcine Circovirus Type 2 and Mycoplasma hyopneumoniae Vaccine in Naturally Infected Farms in Taiwan [PDF]
Veterinary SciencesPorcine circovirus type 2 (PCV2) and Mycoplasma hyopneumoniae (MHP) are both important and common pathogens in the pig industry. Both pathogens are major contributors to the porcine respiratory disease complex and serve to potentiate other bacterial ...
Fu-Chun Hsueh +7 more
doaj +2 more sources
Immunization of pigs with Actinobacillus pleuropneumonia live attenuated (gene-deleted) vaccine HB04M intramuscularly or intranasally exhibits remarkably rapid protection against heterologous strain challenge [PDF]
BMC Veterinary ResearchActinobacillus pleuropneumonia (APP) is the etiological agent of porcine pleuropneumonia, characterized by acute hemorrhagic fibrinous pleuropneumonia and chronic fibrinous necrotizing pleuropneumonia.
Song Qi +8 more
doaj +2 more sources
Serotype diversity of Actinobacillus pleuropneumoniae detected by real-time PCR in clinical and subclinical samples from Spanish pig farms during 2017–2022 [PDF]
Veterinary ResearchActinobacillus pleuropneumoniae is the causative agent of porcine pleuropneumonia, a challenging respiratory disease for the global swine industry. Variations in the serotypes associated with clinical disease have been observed in different regions ...
José Luis Arnal Bernal +6 more
doaj +2 more sources
Phosphorylation of the β2 integrin subunit CD18 contributes to Actinobacillus pleuropneumoniae ApxI-induced cytotoxicity through the downregulation of Akt activity [PDF]
Scientific ReportsActinobacillus pleuropneumoniae, the causative agent of porcine pleuropneumonia, produces various virulence factors, including the exotoxin ApxI, which contributes to disease pathogenesis.
Jia-Ying Wu +6 more
doaj +2 more sources
Novel Soluble apxIVA-Truncated Protein and Its Application to Rapid Detection and Distinction of Actinobacillus pleuropneumoniae Wild-Strain-Infected Samples from Those Vaccinated with apxIV-Partially Deleted Vaccine [PDF]
Veterinary SciencesActinobacillus pleuropneumoniae (APP) is a bacterial pathogen causing porcine pleuropneumonia, causing great economic loss to the global pig industry.
Jing Rao +5 more
doaj +2 more sources
Actinobacillus pleuropneumoniae Serotypes by Multiplex PCR Identification and Evaluation of Lung Lesions in Pigs from Piedmont (Italy) Farms [PDF]
AnimalsPorcine pleuropneumonia (PPP) is one of the main causes leading to massive losses in the pig industry, with high economic impacts. Among different etiological agents, Actinobacillus pleuropneumoniae (APP) is responsible for severe fibrinous-necrotizing ...
Matteo Cuccato +9 more
doaj +2 more sources