Results 141 to 150 of about 26,154 (226)

Unraveling the Complex Dynamics of Porcine Respiratory Disease Complex (PRDC) Pathogens in the Spanish Swine Production

Abstract The porcine respiratory disease complex (PRDC) poses a significant economic burden on global swine production and adversely impacts animal health and welfare due to its multifactorial nature and complex pathogen interactions. Here, through a comprehensive epidemiological analysis of 6,017 clinical cases from Spanish swine farms ...
Gema Chacón-Pérez, Ana I. Pastor-Calonge, Silvia Del Caso-Yagüe, Sonia Martínez-Martínez, José Luis Arnal-Bernal, César B. Gutiérrez-Martín, Alfredo Á. Benito-Zúñiga, Oscar Mencía-Ares   +7 more
openaire   +1 more source

Transdermal Delivery of an mRNA‐Liposome Vaccine via Dissolving Microneedle to Preserve Vaccine Activity and Enhance Immune Activation

Advanced Science, Volume 13, Issue 34, 19 June 2026.
An mRNA‐liposome vaccine via dissolving microneedles (ML‐DMN) enables efficient skin‐targeted delivery while preserving mRNA integrity and allowing sustained antigen expression. Unlike intramuscular (IM) injection, ML‐DMN engages skin‐resident immune cells, activates antigen‐presenting cells (APCs), and induces strong T cell and cytokine responses at ...
Jeehye Nam, JiWon Ahn, Jiwoo Shin, Nahong Lee, Youjin Lee, Sung min Cho, Paul Kim, Geonwoo Kang, Sang‐Jun Ha, Hyungil Jung   +9 more
wiley   +1 more source

Smartly Assembled near‐Micron RF‐Responsive Agents Bridge Transarterial Embolization and Immunothermal Potentiation

Advanced Science, Volume 13, Issue 31, 4 June 2026.
ABSTRACT Hepatocellular carcinoma (HCC) remains a significant clinical challenge due to the limited efficacy of conventional treatments like surgery, radiofrequency ablation (RFA), and transarterial embolization (TAE). Here, we develop an innovative TAE and immunothermal therapy strategy based on smartly assembled near‐micron layered double hydroxide ...
Qitao Hu, Junkang Ding, Lingxiao Zhang, Zhou Tian, Cheng Zeng, Shaomin Zou, Wenjing Zhang, Tangye Zeng, Zhencang Gao, Zhouyi Sun, Gang Liu, Weiyu Chen, Zhe Tang   +12 more
wiley   +1 more source

WSB.APP/PS1 mice develop age‐dependent cerebral amyloid angiopathy, cerebrovascular dysfunction, and white matter deficits

Alzheimer's &Dementia, Volume 22, Issue 6, June 2026.
Abstract INTRODUCTION Cerebrovascular deficits, including cerebral amyloid angiopathy (CAA), play a key role in Alzheimer's disease (AD) pathogenesis. Here, we characterize the susceptibility of the WSB/EiJ genetic context to human AD‐relevant cerebrovascular phenotypes. METHODS CAA and parenchymal plaque analysis and in vivo neurovascular imaging were
Olivia J. Marola, Asli Uyar, Kelly J. Keezer, Juan Antonio K. Chong Chie, Kevin J. Elk, Abigail E. Cullen, Kierra Eldridge, Scott Persohn, Jonathan Nyandu Kanyinda, Jennifer D. Whitesell, Julie A. Harris, Paul Salama, Ashley E. Walker, Gregory W. Carter, Michael Sasner, Paul R. Territo, Gareth R. Howell, Kristen D. Onos   +17 more
wiley   +1 more source

Clinical pharmacology and prescribing education: An updated medical school curriculum from the British Pharmacological Society

British Journal of Clinical Pharmacology, Volume 92, Issue 6, Page 1787-1808, June 2026.
Aims Prescribing is a complex, essential skill that doctors must acquire to practice medicine safely and effectively. The British Pharmacological Society has historically provided a core curriculum to guide clinical pharmacology and prescribing education in UK medical schools.
Dagan O. Lonsdale, Clare Guilding, Jennifer Koenig, Michael Okorie, Reecha Sofat, Simon Maxwell   +5 more
wiley   +1 more source

Porcine reproductive and respiratory syndrome and swine influenza viruses co-infections and superinfections of porcine respiratory cells and tissues

, 2018
Session 1 : Anti-Infectious ImmunityNational audienceIn the pig, respiratory co-infections involving multiple pathogens are more frequent than single infections.
Ménard, Déborah, Bourry, Olivier, Gagnon, Carl A., Meurens, François, Hervet, Caroline, Simon, Gaelle, Belloc, Catherine, C., Saade, Georges, Leblanc-Maridor, Mily, Provost, Chantale   +9 more
core  

Recent Progress on Enzyme Immobilization: Materials, Strategies, and Applications

Food Bioengineering, Volume 5, Issue 2, Page 220-243, June 2026.
Enzyme immobilization technology has undergone substantial evolution driven by advances in materials science. This review systematically examines the recent advances in enzyme immobilization since 2024, with a focused analysis of five major categories of enzyme carriers including covalent organic framework, metal‐organic frameworks, polymers, carbon ...
Shuran Wang, Ruoke Li, Yixuan Xie, Hanya Zhang, Xiaoyu Huang, Siwei Chen, Weixin Xu, Yueling Liu   +7 more
wiley   +1 more source

Epidemiology of Major Bacterial Pathogens Associated with Porcine Respiratory Disease Complex: A Cross-Sectional Study from Intensive Swine Farms in Xinjiang, China (2024-2025). [PDF]

Vet Sci
Guo Y, Li Y, Wen Z, Liang Y, Lian K, Zheng P, Qu Y.   +6 more
europepmc   +1 more source

The Role of Endothelin‐1 in Autoimmune Diseases: Mechanistic Insights and Therapeutic Targets

iNew Medicine, Volume 2, Issue 2, June 2026.
The Role of Endothelin‐1 in Autoimmune Diseases. NF‐κB: nuclear factor kappa‐B; MAPK: mitogen‐activated protein kinase; PI3K: phosphoinositide 3‐kinase; ROS: reactive oxygen species; CTGF: connective tissue growth factor; TGF‐β: transforming growth factor‐β.
Xun Gong, Zhenyu Wang, Suyin Yang, Kaige Gao, Xin Yang, Min Tang   +5 more
wiley   +1 more source