Results 161 to 170 of about 18,671,976 (307)

Pore network modelling of fissured and vuggy carbonates

, 2020
Karbonat kayaçlar, dünya üzerindeki hidrokarbon rezervlerinin büyük bir kısmına sahiptir. Hidrokarbon kurtarımının doğru bir şekilde öngörülmesi için, karbonatların sahip olduğu akış özellikleri doğru tahmin edilmeli ve akış mekanizmaları anlaşılmalıdır.
openaire   +1 more source

Pore-scale analysis of hydrogen-water displacement in sandstones: a comparison of pore-network modelling and flow visualisation experiments

Hydrogen–water displacement in porous rocks involves capillary-dominated multiphase-flow processes at the pore scale that are critical for understanding fluid distribution, trapping, and recovery behaviour. Three-dimensional pore-scale flow visualisation
Bultreys, Tom, Menke, Hannah; id_orcid, Jiang, Zeyun, Foroughi, Sajjad, Busch, Andreas; id_orcid, Singh, Kamaljit; id_orcid, Jangda, Zaid; id_orcid, Geiger, Sebastian, Singh, Kamaljit, Menke, Hannah, Jangda, Zaid, Busch, Andreas   +11 more
core   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

Molecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira, Ana Teixeira‐Marques, Rui Freitas, João A Carvalho, Sara Monteiro‐Reis, Giorgio I. Russo, Rui Henrique, Carmen Jerónimo   +7 more
wiley   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Modeling nanoparticle transport in tumors with a pore network model

, 2019
Ei mogleg tilnærming i kreftbehandling er å innkapsle cytotoksiske medisinar i nanopartiklar for å auke spesifisiteten til medisinane samtidig som systemisk tokisitet blir redusert. Fokusert ultralyd i kombinasjon med nanopartiklar kan auke transporten av medisinar til kvreftsvulstar.
openaire   +1 more source

Fluid-fluid porometry, pore network simulation

, 2018
International audiencePore network modeling used for the simulation of drainage through a porous medium is carried out. A comparison with the results of the parallel tubes model is investigated to better extract the pore-size distribution derived from ...
PRAT, Marc, LASSEUX, Didier, PEINADOR, R, MAALAL, O   +3 more
core  

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

Molecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David, Arthur Karaulic, Audrey Bennetot, Clémence Fournier, Quentin Odet, Arthur Gouraud, Isabelle Bourget, Cédric Gaggioli, Sandy Giuliano, Frédéric Luciano, Olivier Léger, Zaki Sellam, Gilles Pagès   +12 more
wiley   +1 more source

Static Drainage H₂/O₂ PEM Fuel Cells Enabled by Water Transport Plates: Pore-Scale Design and Transport Mechanisms. [PDF]

Adv Sci (Weinh)
Guo M, Qiu D, Zhu D, Peng L.
europepmc   +1 more source