Results 191 to 200 of about 207,601 (314)
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Pressure- and heat-induced insertion of CO2 into an auxetic small-pore zeolite
When the small-pore zeolite natrolite is compressed at ca. 1.5 GPa and heated to ca. 110 °C in the presence of CO2, the unit cell volume of natrolite expands by 6.8% and ca. 12 wt % of CO2 is contained in the expanded elliptical channels.
D Seoung (13726294) +5 more
core
Pore-pressure diffusion, enhanced by poroelastic stresses, controls induced seismicity in Oklahoma. [PDF]
Zhai G, Shirzaei M, Manga M, Chen X.
europepmc +1 more source
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley +1 more source
Rapid tremor migration and pore-pressure waves in subduction zones. [PDF]
Cruz-Atienza VM +3 more
europepmc +1 more source
Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee +6 more
wiley +1 more source
Pore pressure evolution and mass loss of broken gangue during the seepage. [PDF]
Zhang J, Liu Y, Zhou N, Li M.
europepmc +1 more source
Why human connection is the true metric of research success
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan +3 more
wiley +1 more source
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
Episodic creep events on the San Andreas Fault caused by pore-pressure variations. [PDF]
Khoshmanesh M, Shirzaei M.
europepmc +1 more source

